| Literature DB >> 12636405 |
Biao Jiang1, Jia-Feng Liu, Sheng-Yin Zhao.
Abstract
Full details of the total syntheses of slagenins A-C (1a-c) and their antipodes (2a-c), novel bromopyrrole alkaloids with a unique tetrahydrofuro[2,3-d]imidazolidin-2-one moiety, are described in which their absolute stereochemistry was established. The key step in the syntheses involves the efficient condensation of dihydrofuran-3-one or glyoxal with urea to construct the slagenin bicycle core.Entities:
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Year: 2003 PMID: 12636405 DOI: 10.1021/jo026773i
Source DB: PubMed Journal: J Org Chem ISSN: 0022-3263 Impact factor: 4.354