Literature DB >> 12636405

Enantioselective total syntheses of slagenins A-C and their antipodes.

Biao Jiang1, Jia-Feng Liu, Sheng-Yin Zhao.   

Abstract

Full details of the total syntheses of slagenins A-C (1a-c) and their antipodes (2a-c), novel bromopyrrole alkaloids with a unique tetrahydrofuro[2,3-d]imidazolidin-2-one moiety, are described in which their absolute stereochemistry was established. The key step in the syntheses involves the efficient condensation of dihydrofuran-3-one or glyoxal with urea to construct the slagenin bicycle core.

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Year:  2003        PMID: 12636405     DOI: 10.1021/jo026773i

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  3 in total

1.  Asymmetric synthesis of (S)-ethyl-4-chloro-3-hydroxybutanoate using Candida parapsilosis ATCC 7330.

Authors:  Tarjan Kaliaperumal; S Kumar; Sathyanarayana N Gummadi; Anju Chadha
Journal:  J Ind Microbiol Biotechnol       Date:  2009-11-08       Impact factor: 3.346

2.  Gold(I)-Catalyzed Intramolecular Hydroamination of N-Allylic,N'-Aryl Ureas to form Imidazolidin-2-ones.

Authors:  Hao Li; Feijie Song; Ross A Widenhoefer
Journal:  Adv Synth Catal       Date:  2011-04-18       Impact factor: 5.837

3.  Deoxygenation of 5-O-benzoyl-1,2-isopropylidene-3-O-imidazolylthiocarbonyl-α-d-xylofuranose using dimethyl phosphite: an efficient alternate method towards a 3'-deoxynucleoside glycosyl donor.

Authors:  Ivan Zlatev; Jean-Jacques Vasseur; François Morvan
Journal:  Tetrahedron Lett       Date:  2008-03-21       Impact factor: 2.415

  3 in total

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