OBJECTIVE: To determine causes of death in patients with pure polymyalgia rheumatica (PMR) compared to matched population controls. METHODS: In a population based study from 1987-1997, 315 patients were diagnosed with PMR. The patients were each randomly assigned four population controls, totally 1,260 controls. The date and causes of death were identified from the data files at Statistics Norway up to the end of 1997. RESULTS: A total of 65 cases (20.6%) with PMR died compared to 338 (26.8%) among the controls (mortality rate ratio (MRR) = 0.73, 95% CI 0.56-0.97, p = 0.03). No statistically significant difference was found between patients and controls with regard to mortality from coronary heart disease or stroke (MRR=0.78, 95% CI 0.52-1.18), cancer (MRR = 0.59, 95% CI 0.30-1.17), and other causes (MRR=0.75, 95% CI 0.48-1.17). CONCLUSION: The increased survival found in patients with PMR could not be explained by reduction in any particular cause of death.
OBJECTIVE: To determine causes of death in patients with pure polymyalgia rheumatica (PMR) compared to matched population controls. METHODS: In a population based study from 1987-1997, 315 patients were diagnosed with PMR. The patients were each randomly assigned four population controls, totally 1,260 controls. The date and causes of death were identified from the data files at Statistics Norway up to the end of 1997. RESULTS: A total of 65 cases (20.6%) with PMR died compared to 338 (26.8%) among the controls (mortality rate ratio (MRR) = 0.73, 95% CI 0.56-0.97, p = 0.03). No statistically significant difference was found between patients and controls with regard to mortality from coronary heart disease or stroke (MRR=0.78, 95% CI 0.52-1.18), cancer (MRR = 0.59, 95% CI 0.30-1.17), and other causes (MRR=0.75, 95% CI 0.48-1.17). CONCLUSION: The increased survival found in patients with PMR could not be explained by reduction in any particular cause of death.
Authors: Sara Muller; Samantha Hider; Toby Helliwell; Joanne Bailey; Kevin Barraclough; Louise Cope; Bhaskar Dasgupta; Rebecca Foskett; Rhian Hughes; Zoe Mayson; Charlotte Purcell; Edward Roddy; Simon Wathall; Irena Zwierska; Christian D Mallen Journal: BMC Musculoskelet Disord Date: 2012-06-15 Impact factor: 2.362
Authors: Adam T Hancock; Christian D Mallen; Sara Muller; John Belcher; Edward Roddy; Toby Helliwell; Samantha L Hider Journal: CMAJ Date: 2014-07-28 Impact factor: 8.262
Authors: Richard Partington; Toby Helliwell; Sara Muller; Alyshah Abdul Sultan; Christian Mallen Journal: Arthritis Res Ther Date: 2018-11-20 Impact factor: 5.156