Literature DB >> 12635300

Enzymatic cleavage of methotrexate provides a method for prevention of drug toxicity.

B A Chabner1, D G Johns, J R Bertino.   

Abstract

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Year:  1972        PMID： 12635300     DOI： 10.1038/239395b0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  10 in total

1.  Carboxypeptidase displaying differential velocity in hydrolysis of methotrexate, 5-methyltetrahydrofolic acid, and leucovorin.

Authors:  A M Albrecht; E Boldizsar; D J Hutchison
Journal:  J Bacteriol       Date:  1978-05       Impact factor: 3.490

Review 2.  Mechanisms and prediction of drug-induced liver disease.

Authors:  P Berthelot
Journal:  Gut       Date:  1973-04       Impact factor: 23.059

Review 3.  Mechanisms, Management and Prevention of Pemetrexed-Related Toxicity.

Authors:  Nikki de Rouw; Berber Piet; Hieronymus J Derijks; Michel M van den Heuvel; Rob Ter Heine
Journal:  Drug Saf       Date:  2021-11-06       Impact factor: 5.606

4.  Threshold methotrexate concentration for in vivo inhibition of DNA synthesis in normal and tumorous target tissues.

Authors:  B A Chabner; R C Young
Journal:  J Clin Invest       Date:  1973-08       Impact factor: 14.808

5.  Molecular cloning of the Pseudomonas carboxypeptidase G2 gene and its expression in Escherichia coli and Pseudomonas putida.

Authors:  N P Minton; T Atkinson; R F Sherwood
Journal:  J Bacteriol       Date:  1983-12       Impact factor: 3.490

6.  Carboxypeptidase G2 rescue in patients with methotrexate intoxication and renal failure.

Authors:  S Buchen; D Ngampolo; R G Melton; C Hasan; A Zoubek; G Henze; U Bode; G Fleischhack
Journal:  Br J Cancer       Date:  2005-02-14       Impact factor: 7.640

Review 7.  Preventing and Managing Toxicities of High-Dose Methotrexate.

Authors:  Scott C Howard; John McCormick; Ching-Hon Pui; Randall K Buddington; R Donald Harvey
Journal:  Oncologist       Date:  2016-08-05

Review 8.  Drugs and pharmaceuticals: management of intoxication and antidotes.

Authors:  Silas W Smith
Journal:  EXS       Date:  2010

9.  Glucarpidase to combat toxic levels of methotrexate in patients.

Authors:  Jacalyn M Green
Journal:  Ther Clin Risk Manag       Date:  2012-11-22       Impact factor: 2.423

10.  Consensus Guideline for Use of Glucarpidase in Patients with High-Dose Methotrexate Induced Acute Kidney Injury and Delayed Methotrexate Clearance.

Authors:  Laura B Ramsey; Frank M Balis; Maureen M O'Brien; Kjeld Schmiegelow; Jennifer L Pauley; Archie Bleyer; Brigitte C Widemann; David Askenazi; Sharon Bergeron; Anushree Shirali; Stefan Schwartz; Alexander A Vinks; Jesper Heldrup
Journal:  Oncologist       Date:  2017-10-27
  10 in total

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