Literature DB >> 1263404

[The treatment of excessive arterial hypertension by a permanent cardiac pacemaker system: a case report concerning the possibility to influence the disturbed harmonization between the heart and the arterial system (author's transl)].

J Schaefer, M Schöttler.   

Abstract

In a 63 year old female patient with a history of longstanding arterial hypertension the implantation of a permanent cardiac pacemaker system resulted in a drastic reduction of the elevated blood pressure values, allowing to reduce the formerly necessary high dosage of antihypertensive drugs. It can be assumed that in the case presented the insertion of the permanent pacemaker leads to several hemodynamic changes: firstly, the heart rate is elevated slightly, secondly, the course of the ejection of the stroke volume is changed and consequently the contour of the pulse wave. Especially the latter factor may have an influence on various regulating mechanisms of the circulatory system and thereby on the lowering of the arterial blood pressure and the consecutive reduction of the hypertrophy of the left ventricle. Most probably the baroreceptor reflex system may be of additional great importance. In addition the "desynchronization" of the spread of excitation by the cardiac pacer might be assumed to change the action of the heart in the beginning of the ejection phase into a "softer" way of pumping. The alteration of a rather "rigid" pump (during normal excitation) into a "soft" pump (during desynchronized excitation) thus may lead to a lowering of the arterial pressure a) by decreasing the speed of ejection of the stroke volume and b) by improving the matching between the heart and the arterial "Windkessel".

Entities:  

Mesh:

Year:  1976        PMID: 1263404     DOI: 10.1007/BF01468923

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN: 0023-2173


  10 in total

1.  Arterial impedance as ventricular afterload.

Authors:  W R Milnor
Journal:  Circ Res       Date:  1975-05       Impact factor: 17.367

2.  The heritability of blood pressure: an investigation of 200 pairs of twins using the cold pressor test.

Authors:  M L McIlhany; J W Shaffer; E A Hines
Journal:  Johns Hopkins Med J       Date:  1975-02

3.  HAEMODYNAMIC STUDIES IN PATIENTS WITH ARTIFICIAL PACEMAKERS.

Authors:  E SOWTON
Journal:  Br Heart J       Date:  1964-11

4.  Synchronicity of ventricular contraction: observations comparing haemodynamic effects of atrial and ventricular pacing.

Authors:  J P GILMORE; S J SARNOFF; J H MITCHELL; R J LINDEN
Journal:  Br Heart J       Date:  1963-05

Review 5.  [Interrelationship between dynamics and regulation of the arterial system].

Authors:  T Kenner
Journal:  Verh Dtsch Ges Kreislaufforsch       Date:  1974

6.  Permanent cardiac pacing as a possible adjunct for the treatment of hypertensive heart disease with bradycardia.

Authors:  J Schaefer; H J Schwarzkopf; C Pape; M Schöttler
Journal:  Johns Hopkins Med J       Date:  1974-09

7.  [Reduction of elevated systolic blood pressure values associated with bradycardic disturbances of rhythm by increasing heart rate via permanent pacing (author's transl)].

Authors:  J Schaefer; H J Schwarzkopf; C Pape
Journal:  Klin Wochenschr       Date:  1974-02-15

8.  Drug therapy: patient compliance.

Authors:  B Blackwell
Journal:  N Engl J Med       Date:  1973-08-02       Impact factor: 91.245

9.  Hemodynamic consequences of atrial and ventricular pacing in patients with normal and abnormal hearts. Effect of exercise at a fixed atrial and ventricular rate.

Authors:  A Benchimol; J G Ellis; E G Dimond
Journal:  Am J Med       Date:  1965-12       Impact factor: 4.965

10.  Hemodynamic effects of tachycardias produced by atrial and ventricular pacing.

Authors:  P Samet; W H Bernstein; S Levine; A Lopez
Journal:  Am J Med       Date:  1965-12       Impact factor: 4.965

  10 in total

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