Literature DB >> 12633113

Enantioselective cyanosilylation of ketones by a catalytic double-activation method employing chiral Lewis acid and achiral N-oxide catalysts.

Fuxue Chen1, Xiaoming Feng, Bo Qin, Guolin Zhang, Yaozhong Jiang.   

Abstract

[reaction: see text] Enantioselective addition of TMSCN to ketones is achieved by a catalytic double-activation method using 1a-Ti(IV) complex as the Lewis acid and achiral N-oxide 2 as the Lewis base to activate ketones and TMSCN, respectively.

Entities:  

Year:  2003        PMID： 12633113     DOI： 10.1021/ol034158a

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  7 in total

1.  Thiourea-catalyzed enantioselective cyanosilylation of ketones.

Authors:  Douglas E Fuerst; Eric N Jacobsen
Journal:  J Am Chem Soc       Date:  2005-06-29       Impact factor: 15.419

2.  Chiral imine copper chloride-catalyzed enantioselective desymmetrization of 2-substituted 1,2,3-propanetriols.

Authors:  Byunghyuck Jung; Sung Ho Kang
Journal:  Proc Natl Acad Sci U S A       Date:  2007-01-22       Impact factor: 11.205

3.  Synergistic Catalysis: A Powerful Synthetic Strategy for New Reaction Development.

Authors:  Anna E Allen; David W C Macmillan
Journal:  Chem Sci       Date:  2012-01-25       Impact factor: 9.825

4.  Bifunctional asymmetric catalysis: cooperative Lewis acid/base systems.

Authors:  Daniel H Paull; Ciby J Abraham; Michael T Scerba; Ethan Alden-Danforth; Thomas Lectka
Journal:  Acc Chem Res       Date:  2008-04-11       Impact factor: 22.384

5.  Effect of carbonates/phosphates as nucleophilic catalysts in dimethylformamide for efficient cyanosilylation of aldehydes and ketones.

Authors:  G K Surya Prakash; Habiba Vaghoo; Chiradeep Panja; Vijayalakshmi Surampudi; Roman Kultyshev; Thomas Mathew; George A Olah
Journal:  Proc Natl Acad Sci U S A       Date:  2007-02-22       Impact factor: 11.205

6.  The Cyanation of Prochiral Aldehydes with Chiral Copper Complexes of R-(+)/S-(-) -α-Ethylphenyl Amine in Methanol.

Authors:  Luo Mei
Journal:  Curr Org Synth       Date:  2016-06       Impact factor: 1.975

7.  Lanthanide complexes combined with chiral salen ligands: application in the enantioselective epoxidation reaction of α,β-unsaturated ketones.

Authors:  Xuexiu Xia; Chengrong Lu; Bei Zhao; Yingming Yao
Journal:  RSC Adv       Date:  2019-05-03       Impact factor: 4.036
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.