Literature DB >> 12630873

Inert site in a protein zinc cluster: isotope exchange by high resolution mass spectrometry.

Claudia A Blindauer1, Nick C Polfer, Stella E Keiper, Mark D Harrison, Nigel J Robinson, Pat R R Langridge-Smith, Peter J Sadler.   

Abstract

Using electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry, we show that one Zn2+ ion in the Zn4 cluster of cyanobacterial metallothionein is inert to exchange with 67Zn2+. We suggest that this is zinc in site A, which together with the surrounding alpha and beta secondary structure forms a zinc-finger fold.

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Year:  2003        PMID: 12630873     DOI: 10.1021/ja0284409

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  2 in total

Review 1.  Bacterial metallothioneins: past, present, and questions for the future.

Authors:  Claudia A Blindauer
Journal:  J Biol Inorg Chem       Date:  2011-05-19       Impact factor: 3.358

2.  Histidine ligands in bacterial metallothionein enhance cluster stability.

Authors:  Claudia A Blindauer; M Tahir Razi; Dominic J Campopiano; Peter J Sadler
Journal:  J Biol Inorg Chem       Date:  2007-01-03       Impact factor: 3.862

  2 in total

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