Literature DB >> 12629564

Relation of parental history of coronary heart disease to obesity in young adults.

I Grotto1, M Huerta, J D Kark, O Shpilberg, J Meyerovitch.   

Abstract

OBJECTIVE: To assess the association between obesity and parental coronary heart disease (CHD) history.
DESIGN: Analysis of data from an ongoing, large-scale survey on medical status, health behaviour and attitudes.
SUBJECTS: Representative samples of Israeli military personnel upon discharge from compulsory service at age 20-22 y. Overall 14297 men and 11638 women were interviewed and examined upon release from military service between 1989 and 1999. MEASUREMENTS: Data on demographic characteristics, family history of CHD, lifestyle, weight and height were collected. Analysis of variance and logistic regression were used.
RESULTS: Higher mean body mass index (BMI) and obesity (BMI>30 kg/m(2)) were associated with paternal CHD history in both sexes, and with maternal CHD history among men. Offspring of a parent with a positive CHD history had a higher mean BMI (23.22 vs 22.86 kg/m(2), P<0.001) and were more likely to be obese (5.4 vs 3.7%, P<0.001) than offspring of parents with no history of CHD. Multivariate adjustment for demographic and behavioural variables associated with obesity attenuated the association (adjusted odds ratio for obesity 1.37, 95% confidence interval: 1.15, 1.64). When stratified by sex, this association remained statistically significant only among males.
CONCLUSION: Young adults with a parental history of CHD are more likely to be overweight. This high-risk group should be targeted for early preventive activities.

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Mesh:

Year:  2003        PMID: 12629564     DOI: 10.1038/sj.ijo.0802242

Source DB:  PubMed          Journal:  Int J Obes Relat Metab Disord


  7 in total

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