Literature DB >> 1262831

Concentrations of ethanol in two segments of the vascular system.

A J Sedman, P K Wilkinson, J G Wagner.   

Abstract

The time courses of capillary and venous blood concentrations of ethanol after oral administration of 0.30 and 0.34 g/kg doses of ethanol to two normal human subjects indicated that, by interpolation, equal capillary and venous concentrations are reached at only one time, and this time varied with the subject. The capillary/venous blood concentration ratios varied markedly as a function of time in both subjects over the entire observation period of 4 h.

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Year:  1976        PMID: 1262831

Source DB:  PubMed          Journal:  J Forensic Sci        ISSN: 0022-1198            Impact factor:   1.832


  11 in total

Review 1.  The phenomenon and rationale of marked dependence of drug concentration on blood sampling site. Implications in pharmacokinetics, pharmacodynamics, toxicology and therapeutics (Part II).

Authors:  W L Chiou
Journal:  Clin Pharmacokinet       Date:  1989-10       Impact factor: 6.447

Review 2.  Role of variability in explaining ethanol pharmacokinetics: research and forensic applications.

Authors:  Ake Norberg; A Wayne Jones; Robert G Hahn; Johan L Gabrielsson
Journal:  Clin Pharmacokinet       Date:  2003       Impact factor: 6.447

3.  Pharmacokinetics of ethanol after oral administration in the fasting state.

Authors:  P K Wilkinson; A J Sedman; E Sakmar; D R Kay; J G Wagner
Journal:  J Pharmacokinet Biopharm       Date:  1977-06

4.  Fasting and nonfasting blood ethanol concentrations following repeated oral administration of ethanol to one adult male subject.

Authors:  P K Wilkinson; A J Sedman; E Sakmar; Y J Lin; J G Wagner
Journal:  J Pharmacokinet Biopharm       Date:  1977-02

5.  The pharmacokinetics of alcohol in human breath, venous and arterial blood after oral ingestion.

Authors:  E Martin; W Moll; P Schmid; L Dettli
Journal:  Eur J Clin Pharmacol       Date:  1984       Impact factor: 2.953

6.  Ethanol-induced disturbance in human arousal mechanism.

Authors:  I Lehtinen; A H Lang; V Jäntti; A Pakkanen; E Keskinen; T Nyrke; M Lempiäinen
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530

Review 7.  Clinical pharmacokinetics of ethanol.

Authors:  N H Holford
Journal:  Clin Pharmacokinet       Date:  1987-11       Impact factor: 6.447

8.  Steroid metabolism in isolated rat hepatocytes.

Authors:  J A Morais; J G Wagner
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1985 Oct-Dec       Impact factor: 2.441

9.  A new blood-flow pharmacokinetic model for ethanol.

Authors:  J L Rheingold; R E Lindstrom; P K Wilkinson
Journal:  J Pharmacokinet Biopharm       Date:  1981-06

10.  Arterial-venous blood alcohol concentration gradients.

Authors:  P K Wilkinson; J L Rheingold
Journal:  J Pharmacokinet Biopharm       Date:  1981-06
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