Literature DB >> 12623228

Of mouse and man--what is the value of the mouse in predicting gene expression in humans?

Robert A Coleman.   

Abstract

The mouse is the most commonly used mammalian species in biomedical research and is widely regarded as a human surrogate species. In this Editorial, Robert Coleman discusses the validity of this assumption and cautions against the unquestioning acceptance of the mouse an experimental model for drug discovery and development.

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Year:  2003        PMID： 12623228     DOI： 10.1016/s1359-6446(03)02613-8

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  3 in total

1.  What could Dr Finlay and Mr Herriot learn from each other?

Authors:  Bob Michell
Journal:  BMJ       Date:  2005-11-26

2.  A bovine model of respiratory Chlamydia psittaci infection: challenge dose titration.

Authors:  Petra Reinhold; Carola Ostermann; Elisabeth Liebler-Tenorio; Angela Berndt; Anette Vogel; Jacqueline Lambertz; Michael Rothe; Anke Rüttger; Evelyn Schubert; Konrad Sachse
Journal:  PLoS One       Date:  2012-01-27       Impact factor: 3.240

3.  The bovine lung in biomedical research: visually guided bronchoscopy, intrabronchial inoculation and in vivo sampling techniques.

Authors:  Annette Prohl; Carola Ostermann; Markus Lohr; Petra Reinhold
Journal:  J Vis Exp       Date:  2014-07-03       Impact factor: 1.355
  3 in total

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