Literature DB >> 12623194

Analysis of Case II drug transport with radial and axial release from cylinders.

Kosmas Kosmidis1, Eleni Rinaki, Panos Argyrakis, Panos Macheras.   

Abstract

Analysis is presented for Case II drug transport with axial and radial release from cylinders. The previously reported [J. Control Release 5 (1987) 37] relationships for radial release from films and slabs are special cases of the general solution derived in this study. The widely used exponential relation M(t)/M(infinity) = kt(n) describes nicely the first 60% of the fractional release curve when Case II drug transport with axial and radial release from cylinders is operating. Copyright 2003 Elsevier Science B.V.

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Year:  2003        PMID: 12623194     DOI: 10.1016/s0378-5173(03)00030-9

Source DB:  PubMed          Journal:  Int J Pharm        ISSN: 0378-5173            Impact factor:   5.875


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