Literature DB >> 12622413

Signaling from novel splice variants of hormone receptors in cancer.

Wei-Qun Ding1, Laurence J Miller.   

Abstract

A number of splice variants of hormone receptors have recently been described in malignant neoplasms. Signaling by these novel receptor isoforms differ from their wild type counterparts, raising interesting questions as to possible roles in the initiation, progression, and metastatic potential of various tumors. This review summarizes recent findings on the signaling of novel variants of hormone receptors, including human HER-2/neu, the secretin receptor, the CCK-B/gastrin receptor and fibroblast growth factor receptor-2.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12622413     DOI： 10.1385/IJGC:31:1-3:31

Source DB:  PubMed          Journal:  Int J Gastrointest Cancer        ISSN： 1537-3649


  81 in total

1.  A genomic view of alternative splicing.

Authors:  Barmak Modrek; Christopher Lee
Journal:  Nat Genet       Date:  2002-01       Impact factor: 38.330

2.  Dominant-negative mutations in the G-protein-coupled alpha-factor receptor map to the extracellular ends of the transmembrane segments.

Authors:  M Dosil; L Giot; C Davis; J B Konopka
Journal:  Mol Cell Biol       Date:  1998-10       Impact factor: 4.272

3.  Identification of two isoforms of mouse neuropeptide Y-Y1 receptor generated by alternative splicing. Isolation, genomic structure, and functional expression of the receptors.

Authors:  M Nakamura; C Sakanaka; Y Aoki; H Ogasawara; T Tsuji; H Kodama; T Matsumoto; T Shimizu; M Noma
Journal:  J Biol Chem       Date:  1995-12-15       Impact factor: 5.157

4.  Stage-specific changes in SR splicing factors and alternative splicing in mammary tumorigenesis.

Authors:  E Stickeler; F Kittrell; D Medina; S M Berget
Journal:  Oncogene       Date:  1999-06-17       Impact factor: 9.867

Review 5.  Gastrin, CCK, signaling, and cancer.

Authors:  E Rozengurt; J H Walsh
Journal:  Annu Rev Physiol       Date:  2001       Impact factor: 19.318

6.  A truncated intracellular HER2/neu receptor produced by alternative RNA processing affects growth of human carcinoma cells.

Authors:  G K Scott; R Robles; J W Park; P A Montgomery; J Daniel; W E Holmes; J Lee; G A Keller; W L Li; B M Fendly
Journal:  Mol Cell Biol       Date:  1993-04       Impact factor: 4.272

7.  Gastrin induces tyrosine phosphorylation of Shc proteins and their association with the Grb2/Sos complex.

Authors:  C Seva; A Kowalski-Chauvel; J S Blanchet; N Vaysse; L Pradayrol
Journal:  FEBS Lett       Date:  1996-01-02       Impact factor: 4.124

8.  Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling.

Authors:  D Graus-Porta; R R Beerli; N E Hynes
Journal:  Mol Cell Biol       Date:  1995-03       Impact factor: 4.272

9.  The human CCKB/gastrin receptor transfected into rat1 fibroblasts mediates activation of MAP kinase, p74raf-1 kinase, and mitogenesis.

Authors:  T Seufferlein; D J Withers; S Broad; T Herget; J H Walsh; E Rozengurt
Journal:  Cell Growth Differ       Date:  1995-04

Review 10.  Neu and its ligands: from an oncogene to neural factors.

Authors:  E Peles; Y Yarden
Journal:  Bioessays       Date:  1993-12       Impact factor: 4.345
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.