Literature DB >> 12620169

Is topical nifedipine effective for chronic anal fissures?

Dan Merenstein1, Dan Rosenbaum.   

Abstract

Patients in this study showed remarkable improvement when 1.5% lidocaine and 0.3% nifedipine were applied twice daily for 6 weeks. This extremely safe, well tolerated, and effective treatment should provide family physicians with a reliable nonsurgical method for treating chronic anal fissures.

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Year:  2003        PMID: 12620169

Source DB:  PubMed          Journal:  J Fam Pract        ISSN: 0094-3509            Impact factor:   0.493


  2 in total

1.  Effect of polyamidoamine (PAMAM) dendrimers on the in vitro release of water-insoluble nifedipine from aqueous gels.

Authors:  Bharathi Devarakonda; Ning Li; Melgardt M de Villiers
Journal:  AAPS PharmSciTech       Date:  2005-10-24       Impact factor: 3.246

Review 2.  The management of patients with primary chronic anal fissure: a position paper.

Authors:  D F Altomare; G A Binda; S Canuti; V Landolfi; M Trompetto; R D Villani
Journal:  Tech Coloproctol       Date:  2011-05-03       Impact factor: 3.781

  2 in total

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