| Literature DB >> 12619164 |
José L Vizmanos1, María J Larráyoz, Idoya Lahortiga, Filomena Floristán, Carmen Alvarez, María D Odero, Francisco J Novo, María J Calasanz.
Abstract
Recently, it was shown that t(10;16)(q22;p13) fuses the MORF and CREBBP genes in a case of childhood acute myeloid leukemia (AML) M5a, with a complex karyotype containing other rearrangements. Here, we report a new case with the MORF-CREBBP fusion in an 84-year-old patient diagnosed with AML M5b, in which the t(10;16)(q22;p13) was the only cytogenetic aberration. This supports that this is a recurrent pathogenic translocation in AML. Copyright 2003 Wiley-Liss, Inc.Entities:
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Year: 2003 PMID： 12619164 DOI： 10.1002/gcc.10174
Source DB: PubMed Journal: Genes Chromosomes Cancer ISSN： 1045-2257 Impact factor: 5.006