Literature DB >> 12619085

A clinician's view of spinal cord injury.

H Louis Harkey1, Elbert A White, Robert E Tibbs, Duane E Haines.   

Abstract

The primary cause of spinal cord injury (SCI) is automobile collisions, followed by violence, falls, and injuries in sporting events. The patient is most frequently a young male. Regardless of cause and age, SCI is a potentially catastrophic injury. The unique anatomical relationship of the spinal cord, being enclosed in the dural sac within the bony vertebral column, make it venerable to a wide range of traumatic insults. SCI is classified as complete or incomplete with several subclasses arranged under each of these respective headings. The probability of recovery to a functional state is usually better for patients with incomplete injuries. Treatment for SCI involves initially immobilizing the injured vertebral column, medications to prevent secondary injury, and potential surgery to release pressure on the spinal cord and restore stability to the vertebral column. Postsurgical care is directed toward prevention and treatment of secondary complications of SCI such as respiratory failure, deep venous thrombosis, and decubitus ulcers. Advances in these areas are providing patients with a greater probability of recovery, a longer life, and a better quality of life. Research in the clinical and basic sciences is opening new avenues of hope for the spinal cord injury patient. Copyright 2003 Wiley-Liss, Inc.

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Year:  2003        PMID: 12619085     DOI: 10.1002/ar.b.10012

Source DB:  PubMed          Journal:  Anat Rec B New Anat        ISSN: 1552-4906


  9 in total

1.  Comparison of Capability of Human Bone Marrow Mesenchymal Stem Cells and Endometrial Stem Cells to Differentiate into Motor Neurons on Electrospun Poly(ε-caprolactone) Scaffold.

Authors:  Sadegh Shirian; Somayeh Ebrahimi-Barough; Hooshang Saberi; Abbas Norouzi-Javidan; Sayed Mostafa Modarres Mousavi; Mohammad Ali Derakhshan; Babak Arjmand; Jafar Ai
Journal:  Mol Neurobiol       Date:  2015-09-29       Impact factor: 5.590

Review 2.  Progress of mesenchymal stem cell therapy for neural and retinal diseases.

Authors:  Tsz Kin Ng; Veronica R Fortino; Daniel Pelaez; Herman S Cheung
Journal:  World J Stem Cells       Date:  2014-04-26       Impact factor: 5.326

3.  Efficacy of N-acetylcysteine on neuroclinical, biochemical, and histopathological parameters in experimental spinal cord trauma: comparison with methylprednisolone.

Authors:  U Y Çavuş; A Yılmaz; M N Aytekin; G Taburcu; A Albayrak; S Yıldırım; I Ağır
Journal:  Eur J Trauma Emerg Surg       Date:  2013-11-21       Impact factor: 3.693

4.  Neuroprotective effects of N-acetyl-cysteine and acetyl-L-carnitine after spinal cord injury in adult rats.

Authors:  Amar Karalija; Liudmila N Novikova; Paul J Kingham; Mikael Wiberg; Lev N Novikov
Journal:  PLoS One       Date:  2012-07-17       Impact factor: 3.240

5.  Absence of galectin-3 attenuates neuroinflammation improving functional recovery after spinal cord injury.

Authors:  Caio Andrade Prins; Fernanda Martins Almeida; Ana Maria Blanco Martinez
Journal:  Neural Regen Res       Date:  2016-01       Impact factor: 5.135

6.  Evaluation of Traumatic Spinal Cord Injury in a Rat Model Using 99mTc-GA-5 as a Potential In Vivo Tracer.

Authors:  Vanessa Izquierdo-Sánchez; Pablo C Zambrano-Rodríguez; Nadia Peña-Merino; Sirio Bolaños-Puchet; Horacio J Reyes-Alva; Angelina Martínez-Cruz; Saé Muñiz-Hernández; Gabriel Guízar-Sahagún; Luis Alberto Medina
Journal:  Molecules       Date:  2021-11-25       Impact factor: 4.411

Review 7.  Neurotrauma and inflammation: CNS and PNS responses.

Authors:  Bruno Siqueira Mietto; Klauss Mostacada; Ana Maria Blanco Martinez
Journal:  Mediators Inflamm       Date:  2015-03-31       Impact factor: 4.711

8.  Polydatin Protects Bone Marrow Stem Cells against Oxidative Injury: Involvement of Nrf 2/ARE Pathways.

Authors:  Meihui Chen; Yu Hou; Dingkun Lin
Journal:  Stem Cells Int       Date:  2015-12-06       Impact factor: 5.443

9.  Tanshinone IIA promotes the differentiation of bone marrow mesenchymal stem cells into neuronal-like cells in a spinal cord injury model.

Authors:  Xue-Mei Zhang; Jiao Ma; Yang Sun; Bing-Qian Yu; Zhuo-Min Jiao; Duo Wang; Mei-Yu Yu; Jin-Yue Li; Jin Fu
Journal:  J Transl Med       Date:  2018-07-13       Impact factor: 5.531

  9 in total

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