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Literature DB >> 1261885

Relationship of serum gastrin response to lower oesophageal sphincter pressure.

Abstract

The role of gastrin in controlling lower oesophageal sphincter pressure (LESP) has been examined by measurement of LESP and serum gastrin response to a test protein solution and a control solution in humans. Both solutions were associated with significant (P less than 0-005) rise in LESP, but serum gastrin rose significantly (P=0-05) only after the protein solution. The rise in serum gastrin after the protein solution preceded the rise in LESP by 30 minutes. These results suggest that the lower oesophageal sphincter response to feeding may be independent of protein and is unrelated to gastrin release.

Entities: Disease Gene Species

Mesh：

Substances：
Dietary Proteins
Gastrins

Year: 1976 PMID： 1261885 PMCID： PMC1411082 DOI： 10.1136/gut.17.2.144

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

9 in total

1. Radioimmunoassay of gastrin in human serum.

Authors: J Hansky; M D Cain
Journal: Lancet Date: 1969-12-27 Impact factor: 79.321

2. Pathogenesis of lower-esophageal-sphincter incompetence.

Authors: W H Lipshutz; R D Gaskins; W M Lukash; J Sode
Journal: N Engl J Med Date: 1973-07-26 Impact factor: 91.245

3. The response of the lower oesophageal sphincter to a test-meal stimulus.

Authors: A Roszkowski; P Guillou; G R Giles
Journal: Br J Surg Date: 1973-06 Impact factor: 6.939

4. Gastric alkalinization. Effect on lower-esophageal-sphincter pressure and serum gastrin.

Authors: R H Higgs; R D Smyth; D O Castell
Journal: N Engl J Med Date: 1974-09-05 Impact factor: 91.245

5. Preparation of 125 I-labelled synthetic human gastrin I for radioimmunoanalysis.

Authors: F Stadil; J F Rehfeld
Journal: Scand J Clin Lab Invest Date: 1972-12 Impact factor: 1.713

6. Lower esophageal sphincter pressure changes after food ingestion.

Authors: O T Nebel; D O Castell
Journal: Gastroenterology Date: 1972-11 Impact factor: 22.682

7. Action of gastrin on the lower oesophageal sphincter in man.

Authors: G R Giles; M C Mason; C Humphries; C G Clark
Journal: Gut Date: 1969-09 Impact factor: 23.059

8. Hormonal control of gastroesophageal-sphincter strength.

Authors: D O Castell; L D Harris
Journal: N Engl J Med Date: 1970-04-16 Impact factor: 91.245

9. Relationship between changes in plasma gastrin and lower oesophageal sphincter pressure after meals.

Authors: I W McCall; R F Harvey; C J Owens; B G Clendinnen
Journal: Br J Surg Date: 1975-01 Impact factor: 6.939