Literature DB >> 12617650

Chiral ligand-controlled asymmetric conjugate addition of lithium amides to enoates.

Hirohisa Doi1, Takeo Sakai, Mayu Iguchi, Ken-ichi Yamada, Kiyoshi Tomioka.   

Abstract

The external chiral ligand-controlled asymmetric conjugate addition reaction of lithium amides with alpha,beta-unsaturated esters provided beta-amino esters in high yields and high enantioselectivities.

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Year:  2003        PMID： 12617650     DOI： 10.1021/ja029633z

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  5 in total

1.  Discovering New Reactions with N-Heterocyclic Carbene Catalysis.

Authors:  Eric M Phillips; Audrey Chan; Karl A Scheidt
Journal:  Aldrichimica Acta       Date:  2009       Impact factor: 3.667

2.  1,4-addition of lithium diisopropylamide to unsaturated esters: role of rate-limiting deaggregation, autocatalysis, lithium chloride catalysis, and other mixed aggregation effects.

Authors:  Yun Ma; Alexander C Hoepker; Lekha Gupta; Marc F Faggin; David B Collum
Journal:  J Am Chem Soc       Date:  2010-11-10       Impact factor: 15.419

3.  Direct amination of homoenolates catalyzed by N-heterocyclic carbenes.

Authors:  Audrey Chan; Karl A Scheidt
Journal:  J Am Chem Soc       Date:  2008-02-09       Impact factor: 15.419

4.  Selenoxide Elimination Triggers Enamine Hydrolysis to Primary and Secondary Amines: A Combined Experimental and Theoretical Investigation.

Authors:  Giovanni Ribaudo; Marco Bortoli; Erika Oselladore; Alberto Ongaro; Alessandra Gianoncelli; Giuseppe Zagotto; Laura Orian
Journal:  Molecules       Date:  2021-05-08       Impact factor: 4.411

5.  Michael additions of amines to methyl acrylates promoted by microwave irradiation.

Authors:  Jaime Escalante; Manuel Carrillo-Morales; Irma Linzaga
Journal:  Molecules       Date:  2008-02-07       Impact factor: 4.411
  5 in total

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