Literature DB >> 12617542

A retrospective study regarding the treatment of lupoid onychodystrophy in 30 dogs and literature review.

Ralf S Mueller1, Rodney A W Rosychuk, Leonard D Jonas.   

Abstract

The treatment records of 30 dogs with lupoid onychodystrophy were evaluated retrospectively. Dogs were treated with fatty acid supplementation (n=18), doxycycline and niacinamide (n=12), tetracycline and niacinamide (n=10), pentoxifylline (n=6), prednisolone (n=5), azathioprine (n=1), clofazimine (n=1), or with combinations thereof. An excellent response was seen in almost half of the patients treated with tetra- or doxycycline in combination with niacinamide. Six of the dogs were maintained successfully on fatty acid supplementation. Spontaneous remissions and recurrences made evaluation of success rates difficult and emphasized the varied and often unclear etiology and natural course of the syndrome.

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Year:  2003        PMID: 12617542     DOI: 10.5326/0390139

Source DB:  PubMed          Journal:  J Am Anim Hosp Assoc        ISSN: 0587-2871            Impact factor:   1.023


  9 in total

1.  Claw disease in the dog: Does your patient have symmetrical lupoid onychodystrophy (SLO)?

Authors:  Stephen Waisglass
Journal:  Can Vet J       Date:  2018-07       Impact factor: 1.008

2.  Whole Genome Sequencing Reveals Multiple Linked Genetic Variants on Canine Chromosome 12 Associated with Risk for Symmetrical Lupoid Onychodystrophy (SLO) in the Bearded Collie.

Authors:  Liza C Gershony; Janelle M Belanger; Marjo K Hytönen; Hannes Lohi; Anita M Oberbauer
Journal:  Genes (Basel)       Date:  2021-08-19       Impact factor: 4.096

3.  DLA class II alleles are associated with risk for canine symmetrical lupoid onychodystrophy [corrected](SLO).

Authors:  Maria Wilbe; Martine Lund Ziener; Anita Aronsson; Charlotte Harlos; Katarina Sundberg; Elin Norberg; Lisa Andersson; Kerstin Lindblad-Toh; Ake Hedhammar; Göran Andersson; Frode Lingaas
Journal:  PLoS One       Date:  2010-08-23       Impact factor: 3.240

Review 4.  Cutaneous lupus erythematosus in dogs: a comprehensive review.

Authors:  Thierry Olivry; Keith E Linder; Frane Banovic
Journal:  BMC Vet Res       Date:  2018-04-18       Impact factor: 2.741

5.  DLA class II risk haplotypes for autoimmune diseases in the bearded collie offer insight to autoimmunity signatures across dog breeds.

Authors:  Liza C Gershony; Janelle M Belanger; Andrea D Short; Myly Le; Marjo K Hytönen; Hannes Lohi; Thomas R Famula; Lorna J Kennedy; Anita M Oberbauer
Journal:  Canine Genet Epidemiol       Date:  2019-02-15

6.  Novel Locus Associated with Symmetrical Lupoid Onychodystrophy in the Bearded Collie.

Authors:  Liza C Gershony; Janelle M Belanger; Marjo K Hytönen; Hannes Lohi; Anita M Oberbauer
Journal:  Genes (Basel)       Date:  2019-08-22       Impact factor: 4.096

7.  Genetics and epidemiology of hypothyroidism and symmetrical onychomadesis in the Gordon setter and the English setter.

Authors:  Martine Lund Ziener; Stina Dahlgren; Stein Istre Thoresen; Frode Lingaas
Journal:  Canine Genet Epidemiol       Date:  2015-08-21

8.  A treatment study of canine symmetrical onychomadesis (symmetrical lupoid onychodystrophy) comparing fish oil and cyclosporine supplementation in addition to a diet rich in omega-3 fatty acids.

Authors:  Martine L Ziener; Ane Nødtvedt
Journal:  Acta Vet Scand       Date:  2014-10-04       Impact factor: 1.695

9.  Effects of pentoxifylline on whole blood IL-2 and IFN-gamma gene expression in normal dogs.

Authors:  Evangel Kummari; Andres Gibbs; Caitlin Riggs; Claire Fellman; John Stokes; John Thomason; Robert Wills; Andrew Mackin; Todd Archer
Journal:  Vet Med Sci       Date:  2019-10-16
  9 in total

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