| Literature DB >> 12617512 |
Koji Nagai1, Kazuma Kamigiri, Hisao Matsumoto, Yasuhiro Kawano, Masakazu Yamaoka, Hitoshi Shimoi, Masato Watanabe, Kenichi Suzuki.
Abstract
A new antifungal antibiotic, YM-202204 (1), was found in the culture broth of marine fungus Phoma sp. Q60596. The structure of 1 was determined by several spectroscopic experiments as a new lactone compound. This antibiotic exhibited potent antifungal activities against Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus, and also inhibited glycosyl-phosphatidyl-inositol (GPI)-anchoring in yeast cells.Entities:
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Year: 2002 PMID： 12617512 DOI： 10.7164/antibiotics.55.1036
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649