Literature DB >> 12617416

Recognising severe pneumonia with simple clinical and biochemical measurements.

A Kamath1, M C Pasteur, M G Slade, B D W Harrison.   

Abstract

Community-acquired pneumonia (CAP) is the most common reason for acute admission to hospital and the fourth most common cause of death in the UK. It is important to identify patients with severe pneumonia and the worst prognosis. We conducted this study to validate a rule designed to do this devised in New Zealand. CAP was defined by evidence of new shadowing on the chest X-ray and clinical features of pneumonia. A standardised proforma was completed documenting clinical features and investigation results. Severe pneumonia was identified by two or more of the following: confusion; respiratory rate > or = 30/min; diastolic blood pressure < or = 60 mmHg; urea >7 mmol/l. One hundred patients (mean age 58.8 years) were included; 32 satisfied the rule. Seven died, all of whom satisfied the rule. Ten patients received intensive care, including six who died. Of 11 patients who died and/or received intensive care, nine satisfied the rule. The sensitivity and specificity of the rule for predicting death and/or intensive care were 82% and 73% respectively.

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Year:  2003        PMID: 12617416      PMCID: PMC4953359          DOI: 10.7861/clinmedicine.3-1-54

Source DB:  PubMed          Journal:  Clin Med (Lond)        ISSN: 1470-2118            Impact factor:   2.659


  8 in total

1.  Simple modification of CURB-65 better identifies patients including the elderly with severe CAP.

Authors:  Phyo K Myint; Ajay V Kamath; Sarah L Vowler; Brian D W Harrison
Journal:  Thorax       Date:  2007-11       Impact factor: 9.139

Review 2.  Defining severe pneumonia.

Authors:  Samuel M Brown; Nathan C Dean
Journal:  Clin Chest Med       Date:  2011-07-12       Impact factor: 2.878

Review 3.  Defining and predicting severe community-acquired pneumonia.

Authors:  Samuel M Brown; Nathan C Dean
Journal:  Curr Opin Infect Dis       Date:  2010-04       Impact factor: 4.915

4.  Validation of the Infectious Disease Society of America/American Thoracic Society 2007 guidelines for severe community-acquired pneumonia.

Authors:  Samuel M Brown; Barbara E Jones; Al R Jephson; Nathan C Dean
Journal:  Crit Care Med       Date:  2009-12       Impact factor: 7.598

5.  Physiological-social score (PMEWS) vs. CURB-65 to triage pandemic influenza: a comparative validation study using community-acquired pneumonia as a proxy.

Authors:  Kirsty Challen; John Bright; Andrew Bentley; Darren Walter
Journal:  BMC Health Serv Res       Date:  2007-03-01       Impact factor: 2.655

6.  The usefulness of confusion, urea, respiratory rate, and shock index or adjusted shock index criteria in predicting combined mortality and/or ICU admission compared to CURB-65 in community-acquired pneumonia.

Authors:  James P Curtain; Prasanna Sankaran; Ajay V Kamath; Phyo K Myint
Journal:  Biomed Res Int       Date:  2013-08-20       Impact factor: 3.411

7.  Clinical Usefulness of Urinary Fatty Acid Binding Proteins in Assessing the Severity and Predicting Treatment Response of Pneumonia in Critically Ill Patients: A Cross-Sectional Study.

Authors:  Tsung-Cheng Tsao; Han-Chen Tsai; Shi-Chuan Chang
Journal:  Medicine (Baltimore)       Date:  2016-05       Impact factor: 1.889

Review 8.  Prediction of severe community-acquired pneumonia: a systematic review and meta-analysis.

Authors:  Christophe Marti; Nicolas Garin; Olivier Grosgurin; Antoine Poncet; Christophe Combescure; Sebastian Carballo; Arnaud Perrier
Journal:  Crit Care       Date:  2012-07-27       Impact factor: 9.097

  8 in total

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