Literature DB >> 12617382

The effect of physical exercise following acute disease exacerbation in patients with dermato/polymyositis.

Cecília Varjú1, Edit Pethö, Réka Kutas, László Czirják.   

Abstract

OBJECTIVE: To study the effect of physical exercise shortly after an acute episode of dermato/polymyositis (DM/PM).
DESIGN: Pilot study of a descriptive nature.
SETTING: Rehabilitation unit of a large general hospital.
SUBJECTS: Ten patients 2-3 weeks after an acute phase of DM/PM (early recovery group) and 11 patients in the inactive stage of DM/PM for at least three months (chronic stage group).
INTERVENTIONS: Isotonic muscle training consisted of several series of different repeated movements at 65-70% of individual maximal repetition limit. Special training was applied for the respiratory muscles. Relaxing baths, mud packs and massages were also applied. OUTCOME MEASURES: Dynamometer and spirometer were used for measuring the changes in muscle strength and respiratory function. Disability tests were done before and after therapy.
RESULTS: No disease relapses or decreases in muscle function were seen. In the early recovery group, the average muscle strength improvement was 17 +/- 31 % (p > 0.05) in the proximal muscles and 37 +/- 23% (p < 0.05) in the distal muscles, while the vital capacity also increased by 17 +/- 21% (p < 0.05). In the chronic stage group the average improvement in muscle strength was 46 +/- 34% (p < 0.05) in the proximal muscles and 37 +/- 29% (p < 0.05) in the distal muscles. By the end of the therapy both groups showed improvements in disability tests (p < 0.05).
CONCLUSIONS: Physical training started 2-3 weeks following an acute exacerbation of the disease seems to be useful and safe. Some improvement in muscle strength and respiratory function can be obtained, muscle atrophy due to inactivity may be partially prevented and the level of disability can be decreased.

Entities:  

Mesh:

Year:  2003        PMID: 12617382     DOI: 10.1191/0269215503cr572oa

Source DB:  PubMed          Journal:  Clin Rehabil        ISSN: 0269-2155            Impact factor:   3.477


  23 in total

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Review 2.  Exercise: an important component of treatment in the idiopathic inflammatory myopathies.

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Review 4.  Exercise as an anti-inflammatory therapy for rheumatic diseases-myokine regulation.

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Review 7.  Idiopathic inflammatory myopathies.

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8.  Upregulation of MHC class I in transgenic mice results in reduced force-generating capacity in slow-twitch muscle.

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Review 9.  New insights into the benefits of exercise for muscle health in patients with idiopathic inflammatory myositis.

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Review 10.  Inflammatory muscle disease: clinical presentation and assessment of patients.

Authors:  Helene Alexanderson; Ingrid E Lundberg
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