Literature DB >> 12616166

Quality of life in surgical treatment of metastatic spine disease.

Eugene K Wai1, Joel A Finkelstein, Ronald P Tangente, Lori Holden, Edward Chow, Michael Ford, Albert Yee.   

Abstract

STUDY
DESIGN: Overall quality of life after surgical management of metastatic disease of the spine was prospectively assessed using a validated global health status quality-of-life instrument-the Edmonton Symptom Assessment Scale.
OBJECTIVES: To prospectively evaluate the efficacy of surgery in patients with metastatic spinal disease with respect to quality of life. SUMMARY OF BACKGROUND DATA: Management of spinal metastases is palliative and is aimed at improving quality of life at an acceptable risk. Although previous studies have evaluated physical outcomes, improvements in pain, and neurologic function after surgery, a multidimensional assessment of quality of life is more relevant in the palliative patient.
METHODS: Twenty-five consecutive patients undergoing surgery for spinal metastases were prospectively evaluated. Pre- and postoperative assessments were performed using the Edmonton Symptom Assessment Scale. The surgical procedure consisted of decompression and instrumented stabilization.
RESULTS: After surgery, the largest improvement was noted in the domain of pain (P < 0.00001). There were also significant improvements noted in the domains of tiredness (P = 0.004), nausea (P = 0.01), anxiety (P = 0.006), drowsiness (P = 0.044), appetite (P = 0.02), and well-being (P = 0.004).
CONCLUSIONS: The current study demonstrates that in the appropriate patient, surgical management brings about a positive effect on the overall quality of life in patients with spinal metastases. The greatest benefit occurred in the reduction of a patient's level of pain.

Entities:  

Mesh:

Year:  2003        PMID: 12616166     DOI: 10.1097/01.BRS.0000048646.26222.FA

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  33 in total

1.  A meta-analysis of surgery versus conventional radiotherapy for the treatment of metastatic spinal epidural disease.

Authors:  Paul Klimo; Clinton J Thompson; John R W Kestle; Meic H Schmidt
Journal:  Neuro Oncol       Date:  2005-01       Impact factor: 12.300

Review 2.  [Prognosis scores for spinal metastases].

Authors:  N H von der Höh; J Gulow; S K Tschöke; A Völker; C E Heyde
Journal:  Orthopade       Date:  2013-09       Impact factor: 1.087

Review 3.  Review of metastatic spine tumour classification and indications for surgery: the consensus statement of the Global Spine Tumour Study Group.

Authors:  David Choi; A Crockard; C Bunger; J Harms; N Kawahara; C Mazel; R Melcher; K Tomita
Journal:  Eur Spine J       Date:  2009-12-29       Impact factor: 3.134

4.  Predictors of quality of life improvement after surgery for metastatic tumors of the spine: prospective cohort study.

Authors:  Ori Barzilai; Lily McLaughlin; Mary-Kate Amato; Anne S Reiner; Shahiba Q Ogilvie; Eric Lis; Yoshiya Yamada; Mark H Bilsky; Ilya Laufer
Journal:  Spine J       Date:  2017-11-06       Impact factor: 4.166

5.  Surgery improves pain, function and quality of life in patients with spinal metastases: a prospective study on 118 patients.

Authors:  Gerald M Y Quan; Jean-Marc Vital; Nicholas Aurouer; Ibrahim Obeid; Jean Palussière; Abou Diallo; Vincent Pointillart
Journal:  Eur Spine J       Date:  2011-06-26       Impact factor: 3.134

6.  The era of stereotactic body radiotherapy for spinal metastases and the multidisciplinary management of complex cases.

Authors:  Rachit Kumar; Anick Nater; Ahmed Hashmi; Sten Myrehaug; Young Lee; Lijun Ma; Kristin Redmond; Simon S Lo; Eric L Chang; Albert Yee; Charles G Fisher; Michael G Fehlings; Arjun Sahgal
Journal:  Neurooncol Pract       Date:  2015-07-27

7.  Predictive value of seven preoperative prognostic scoring systems for spinal metastases.

Authors:  Andreas Leithner; Roman Radl; Gerald Gruber; Markus Hochegger; Katharina Leithner; Heike Welkerling; Peter Rehak; Reinhard Windhager
Journal:  Eur Spine J       Date:  2008-09-12       Impact factor: 3.134

8.  [Surgical management of vertebral column metastatic disease].

Authors:  K-D Schaser; I Melcher; T Mittlmeier; A Schulz; J H Seemann; N P Haas; A C Disch
Journal:  Unfallchirurg       Date:  2007-02       Impact factor: 1.000

Review 9.  Spinal metastasis in the elderly.

Authors:  Max Aebi
Journal:  Eur Spine J       Date:  2003-09-23       Impact factor: 3.134

10.  Evaluation of prognostic scoring systems for spinal metastases in 196 patients treated during 2005-2010.

Authors:  M Dardic; Christine Wibmer; A Berghold; L Stadlmueller; E V Froehlich; A Leithner
Journal:  Eur Spine J       Date:  2014-08-01       Impact factor: 3.134

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