BACKGROUND: Type-specific serological tests have allowed for a better understanding of the epidemiology of herpes simplex virus type 2 (HSV-2) infection in Africa. GOAL: The goal was to determine risk factors for HSV-2 among bar and hotel workers in Moshi, Tanzania. STUDY DESIGN: A cross-sectional study was conducted involving 515 workers in randomly selected bars and hotels in Moshi. RESULTS: The seroprevalence of HSV-2 was 43.5%. Women were more likely to be HSV-2-seropositive than men (age-adjusted OR = 3.8; 95% CI = 2.5-5.8). In multivariate analyses, age was positively associated with HSV-2 in both women and men. HIV-1-seropositive women had a significantly increased risk of HSV-2 infection (adjusted OR = 2.8; 95% CI = 1.5-5.1). Other predictors of HSV-2 were religion and sexual behavior for women and level of education, frequency of alcohol use, and concurrent partners for men. CONCLUSION: The most common genital infection was that with HSV-2. Control of HSV-2 might be an important strategy for HIV-1 infection prevention in this population.
BACKGROUND: Type-specific serological tests have allowed for a better understanding of the epidemiology of herpes simplex virus type 2 (HSV-2) infection in Africa. GOAL: The goal was to determine risk factors for HSV-2 among bar and hotel workers in Moshi, Tanzania. STUDY DESIGN: A cross-sectional study was conducted involving 515 workers in randomly selected bars and hotels in Moshi. RESULTS: The seroprevalence of HSV-2 was 43.5%. Women were more likely to be HSV-2-seropositive than men (age-adjusted OR = 3.8; 95% CI = 2.5-5.8). In multivariate analyses, age was positively associated with HSV-2 in both women and men. HIV-1-seropositive women had a significantly increased risk of HSV-2 infection (adjusted OR = 2.8; 95% CI = 1.5-5.1). Other predictors of HSV-2 were religion and sexual behavior for women and level of education, frequency of alcohol use, and concurrent partners for men. CONCLUSION: The most common genital infection was that with HSV-2. Control of HSV-2 might be an important strategy for HIV-1 infection prevention in this population.
Authors: R K Rana; J M Pimenta; D M Rosenberg; T Warren; S Sekhin; S F Cook; N J Robinson Journal: Sex Transm Infect Date: 2006-02 Impact factor: 3.519
Authors: Deborah Watson-Jones; Helen A Weiss; Mary Rusizoka; Kathy Baisley; Kokugonza Mugeye; John Changalucha; Dean Everett; Rebecca Balira; Louise Knight; David Ross; Richard J Hayes Journal: J Acquir Immune Defic Syndr Date: 2007-12-15 Impact factor: 3.731
Authors: Deborah Watson-Jones; Helen A Weiss; Mary Rusizoka; John Changalucha; Kathy Baisley; Kokugonza Mugeye; Clare Tanton; David Ross; Dean Everett; Tim Clayton; Rebecca Balira; Louise Knight; Ian Hambleton; Jerome Le Goff; Laurent Belec; Richard Hayes Journal: N Engl J Med Date: 2008-03-12 Impact factor: 91.245
Authors: Elia J Mmbaga; Akhtar Hussain; Germana H Leyna; Kagoma S Mnyika; Noel E Sam; Knut-Inge Klepp Journal: BMC Public Health Date: 2007-04-19 Impact factor: 3.295