Literature DB >> 1261599

Interaction between lanthanum and calcium in isolated guinea-pig heart.

P Y Wong, J C Hwang, C H Yeung.   

Abstract

The effect of lanthanum ion on the contraction of the perfused guinea-pig heart has been investigated. Lanthanum caused inhibition of the contractile force. The dose-response curves suggest that there is more than one site with which lanthanum may interact. The high affinity interaction is antagonised by high external calcium. The possibility that a low concentration of lanthanum may block calcium entry into the myocardium is discussed.

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Year:  1976        PMID: 1261599     DOI: 10.1016/0014-2999(76)90281-8

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  2 in total

1.  Extra- and intracellular lanthanum: modified calcium distribution, inward currents and contractility in guinea pig ventricular preparations.

Authors:  M F Wendt-Gallitelli; G Isenberg
Journal:  Pflugers Arch       Date:  1985-12       Impact factor: 3.657

2.  Effects of divalent and lanthanide ions on motility initiation in rat caudal epididymal spermatozoa.

Authors:  W M Lee; A Y Tsang; P Y Wong
Journal:  Br J Pharmacol       Date:  1981-07       Impact factor: 8.739

  2 in total

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