Literature DB >> 12615849

The mechanisms that control intracellular penetration of the HIV protease inhibitors.

Patrick G Hoggard1, Andrew Owen.   

Abstract

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Year:  2003        PMID: 12615849     DOI: 10.1093/jac/dkg137

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN: 0305-7453            Impact factor:   5.790


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  16 in total

1.  Population pharmacokinetics of imatinib and the role of alpha-acid glycoprotein.

Authors:  N Widmer; L A Decosterd; C Csajka; S Leyvraz; M A Duchosal; A Rosselet; B Rochat; C B Eap; H Henry; J Biollaz; T Buclin
Journal:  Br J Clin Pharmacol       Date:  2006-07       Impact factor: 4.335

2.  Potent HIV-1 Protease Inhibitors Containing Carboxylic and Boronic Acids: Effect on Enzyme Inhibition and Antiviral Activity and Protein-Ligand X-ray Structural Studies.

Authors:  Arun K Ghosh; Zilei Xia; Satish Kovela; William L Robinson; Megan E Johnson; Daniel W Kneller; Yuan-Fang Wang; Manabu Aoki; Yuki Takamatsu; Irene T Weber; Hiroaki Mitsuya
Journal:  ChemMedChem       Date:  2019-10-04       Impact factor: 3.466

3.  Ultra-fast analysis of plasma and intracellular levels of HIV protease inhibitors in children: a clinical application of MALDI mass spectrometry.

Authors:  Jeroen J A van Kampen; Mariska L Reedijk; Peter C Burgers; Lennard J M Dekker; Nico G Hartwig; Ineke E van der Ende; Ronald de Groot; Albert D M E Osterhaus; David M Burger; Theo M Luider; Rob A Gruters
Journal:  PLoS One       Date:  2010-07-01       Impact factor: 3.240

4.  Simultaneous population pharmacokinetic model for lopinavir and ritonavir in HIV-infected adults.

Authors:  José Moltó; Manuel José Barbanoj; Cristina Miranda; Asunción Blanco; José Ramón Santos; Eugenia Negredo; Joan Costa; Pere Domingo; Bonaventura Clotet; Marta Valle
Journal:  Clin Pharmacokinet       Date:  2008       Impact factor: 6.447

5.  Selective Targeting of Cells via Bispecific Molecules That Exploit Coexpression of Two Intracellular Proteins.

Authors:  Bryan M Dunyak; Robert L Nakamura; Alan D Frankel; Jason E Gestwicki
Journal:  ACS Chem Biol       Date:  2015-09-02       Impact factor: 5.100

6.  P2' benzene carboxylic acid moiety is associated with decrease in cellular uptake: evaluation of novel nonpeptidic HIV-1 protease inhibitors containing P2 bis-tetrahydrofuran moiety.

Authors:  Ravikiran S Yedidi; Kenji Maeda; W Sean Fyvie; Melinda Steffey; David A Davis; Ira Palmer; Manabu Aoki; Joshua D Kaufman; Stephen J Stahl; Harisha Garimella; Debananda Das; Paul T Wingfield; Arun K Ghosh; Hiroaki Mitsuya
Journal:  Antimicrob Agents Chemother       Date:  2013-07-22       Impact factor: 5.191

7.  Direct effect of human immunodeficiency virus protease inhibitors on neutrophil function and apoptosis via calpain inhibition.

Authors:  Nurit Hadad; Rachel Levy; Francisc Schlaeffer; Klaris Riesenberg
Journal:  Clin Vaccine Immunol       Date:  2007-09-12

8.  Intracellular 'boosting' of darunavir using known transport inhibitors in primary PBMC.

Authors:  Wai San Kwan; Omar Janneh; Ruben Hartkoorn; Becky Chandler; Saye Khoo; David Back; Andrew Owen
Journal:  Br J Clin Pharmacol       Date:  2009-09       Impact factor: 4.335

9.  Intracellular and plasma pharmacokinetics of saquinavir-ritonavir, administered at 1,600/100 milligrams once daily in human immunodeficiency virus-infected patients.

Authors:  Jennifer Ford; Marta Boffito; Adrian Wildfire; Andrew Hill; David Back; Saye Khoo; Mark Nelson; Graeme Moyle; Brian Gazzard; Anton Pozniak
Journal:  Antimicrob Agents Chemother       Date:  2004-07       Impact factor: 5.191

10.  Sensitive enzyme immunoassay for measuring plasma and intracellular nevirapine levels in human immunodeficiency virus-infected patients.

Authors:  Stéphane Azoulay; Marie-Claire Nevers; Christophe Créminon; Laurence Heripret; Jacques Durant; Pierre Dellamonica; Jacques Grassi; Roger Guedj; Danièle Duval
Journal:  Antimicrob Agents Chemother       Date:  2004-01       Impact factor: 5.191

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