| Literature DB >> 12615679 |
Robert J Aiello1, Dominique Brees, Omar L Francone.
Abstract
Studies with ATP-binding cassette transporter (ABCA1)-deficient mice have been critical in demonstrating the relation between ABCA1 expression, cellular lipid efflux, and HDL metabolism. The phenotype of the ABCA1-deficient mouse parallels the phenotype observed in human Tangier disease, including substantial reductions in both apolipoprotein B and apolipoprotein AI with confounding affects on atherosclerosis.Entities:
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Year: 2003 PMID: 12615679 DOI: 10.1161/01.ATV.0000054661.21499.FB
Source DB: PubMed Journal: Arterioscler Thromb Vasc Biol ISSN: 1079-5642 Impact factor: 8.311