Literature DB >> 12615569

Low dose amiodarone causing pseudo-alcoholic cirrhosis.

Amitalh Singhal1, Partha Ghosh, Shahid Anis Khan.   

Abstract

Amiodarone is a commonly used anti-arrhythmic in elderly patients. Abnormal liver function is frequently reported with its use but clinically symptomatic disease is rare. Hepatomegaly, cholestasis, acute hepatitis and rarely fulminant liver failure have been recorded [1, 2], however amiodarone toxicity presenting with cirrhosis is exceedingly rare. Toxic effects of amiodarone are well described with higher dosage but severe hepatic toxicity and cirrhosis with low dose amiodarone has not been reported in the English language literature. We present a report on a patient with pseudo-alcoholic cirrhosis with low dose amiodarone.

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Year:  2003        PMID: 12615569     DOI: 10.1093/ageing/32.2.224

Source DB:  PubMed          Journal:  Age Ageing        ISSN: 0002-0729            Impact factor:   10.668


  6 in total

1.  Liver cirrhosis induced by long-term administration of a daily low dose of amiodarone: a case report.

Authors:  Hiroki Oikawa; Chihaya Maesawa; Ryo Sato; Kanta Oikawa; Hiroyuki Yamada; Seizo Oriso; Sadahide Ono; Akiko Yashima-Abo; Koji Kotani; Kazuyuki Suzuki; Tomoyuki Masuda
Journal:  World J Gastroenterol       Date:  2005-09-14       Impact factor: 5.742

2.  Mitochondrial dysfunction and delayed hepatotoxicity: another lesson from troglitazone.

Authors:  N L Julie; I M Julie; A I Kende; G L Wilson
Journal:  Diabetologia       Date:  2008-08-23       Impact factor: 10.122

3.  Severe cholestatic jaundice in the elderly induced by low-dose amiodarone.

Authors:  Nimer Assy; G Khair; Sorina Schlesinger; Osamah Hussein
Journal:  Dig Dis Sci       Date:  2004-03       Impact factor: 3.487

Review 4.  Gastrointestinal Side Effects of Antiarrhythmic Medications: A Review of Current Literature.

Authors:  Waseem Amjad; Waqas Qureshi; Ali Farooq; Umair Sohail; Salma Khatoon; Sarah Pervaiz; Pratyusha Narra; Syeda M Hasan; Farman Ali; Aman Ullah; Steven Guttmann
Journal:  Cureus       Date:  2017-09-03

5.  Amiodarone Alters Cholesterol Biosynthesis through Tissue-Dependent Inhibition of Emopamil Binding Protein and Dehydrocholesterol Reductase 24.

Authors:  Luke B Allen; Thiago C Genaro-Mattos; Allison Anderson; Ned A Porter; Károly Mirnics; Zeljka Korade
Journal:  ACS Chem Neurosci       Date:  2020-04-29       Impact factor: 4.418

6.  Amiodarone-induced cirrhosis of liver: what predicts mortality?

Authors:  Nasir Hussain; Anirban Bhattacharyya; Suartcha Prueksaritanond
Journal:  ISRN Cardiol       Date:  2013-03-14
  6 in total

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