Literature DB >> 12615190

Hypothalamic-pituitary-adrenal alterations in PTSD: are they relevant to understanding cortisol alterations in cancer?

Rachel Yehuda1.   

Abstract

Recent studies of hypothalamic-pituitary-adrenal axis alterations in PTSD have demonstrated a specific type of hyperresponsivity of this stress hormonal system characterized by a greater negative feedback inhibition of cortisol, which may paradoxically serve to lower cortisol levels. The occurrence of cancer has been recently described by many investigators as an event that fulfills the DSM-IV criteria for a "traumatic event" that has been demonstrated in some cases to be linked with the subsequent development of PTSD. This review considers the extent to which neuroendocrine alterations observed in PTSD may be useful in understanding cortisol alterations involved in cancer.

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Year:  2003        PMID： 12615190     DOI： 10.1016/s0889-1591(02)00070-3

Source DB:  PubMed          Journal:  Brain Behav Immun        ISSN： 0889-1591            Impact factor:   7.217


  9 in total

1.  Psychosocial influences on immunity, including effects on immune maturation and senescence.

Authors:  Christopher L Coe; Mark L Laudenslager
Journal:  Brain Behav Immun       Date:  2007-08-15       Impact factor: 7.217

2.  Symptom severity predicts degree of T cell activation in adult women following childhood maltreatment.

Authors:  Andrine Lemieux; Christopher L Coe; Molly Carnes
Journal:  Brain Behav Immun       Date:  2008-04-18       Impact factor: 7.217

Review 3.  Post-traumatic stress disorder and cancer.

Authors:  Matthew J Cordova; Michelle B Riba; David Spiegel
Journal:  Lancet Psychiatry       Date:  2017-01-19       Impact factor: 27.083

4.  The association between alcohol abuse and neuroendocrine system dysregulation: Race differences in a National sample.

Authors:  Yusuf Ransome; Natalie Slopen; Oskar Karlsson; David R Williams
Journal:  Brain Behav Immun       Date:  2017-07-24       Impact factor: 7.217

5.  Dysregulation of diurnal cortisol secretion affects abstinence induction during a lead-in period of a clinical trial for depressed cocaine-dependent patients.

Authors:  Wilfrid Noel Raby; Lisa Sanfilippo; Martina Pavlicova; Kenneth M Carpenter; Andrew Glass; Chukwudi Onyemekwu; Eric Roginek; Edward V Nunes
Journal:  Am J Addict       Date:  2013-05-30

6.  Post-traumatic disorder symptoms and blunted diurnal cortisol production in partners of prostate cancer patients.

Authors:  Kamala S Thomas; Julienne E Bower; Timothy J Williamson; Michael A Hoyt; David Wellisch; Annette L Stanton; Michael Irwin
Journal:  Psychoneuroendocrinology       Date:  2012-01-03       Impact factor: 4.905

7.  Stress management intervention reduces serum cortisol and increases relaxation during treatment for nonmetastatic breast cancer.

Authors:  Kristin M Phillips; Michael H Antoni; Suzanne C Lechner; Bonnie B Blomberg; Maria M Llabre; Eli Avisar; Stefan Glück; Robert DerHagopian; Charles S Carver
Journal:  Psychosom Med       Date:  2008-10-08       Impact factor: 4.312

8.  Cognitive behavioral stress management effects on psychosocial and physiological adaptation in women undergoing treatment for breast cancer.

Authors:  Michael H Antoni; Suzanne Lechner; Alain Diaz; Sara Vargas; Heather Holley; Kristin Phillips; Bonnie McGregor; Charles S Carver; Bonnie Blomberg
Journal:  Brain Behav Immun       Date:  2008-09-20       Impact factor: 7.217

9.  Hypocortisolism in survivors of severe acute respiratory syndrome (SARS).

Authors:  Melvin Khee-Shing Leow; Daniel Seow-Khee Kwek; Alan Wei-Keong Ng; Kian-Chung Ong; Gregory Jon-Leng Kaw; Lawrence Soon-U Lee
Journal:  Clin Endocrinol (Oxf)       Date:  2005-08       Impact factor: 3.478
  9 in total

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