Literature DB >> 12614493

The Transplant Effects Questionnaire (TxEQ): The development of a questionnaire for assessing the multidimensional outcome of organ transplantation - example of end stage renal disease (ESRD).

J. P. Ziegelmann1, K. Griva, M. Hankins, M. Harrison, A. Davenport, D. Thompson, S. P. Newman.   

Abstract

OBJECTIVES: To develop a questionnaire to assess the responses of transplant recipients to the receipt of an organ, including their self-care behaviour.
DESIGN: Following a literature review, open-ended interviews and a focus group, a transplant questionnaire was developed. Two studies (Study 1: N = 231, Study 2: N = 105) were conducted to evaluate its psychometric properties.
METHODS: A pool of 51 items was derived from themes identified in published studies and from interviews and a focus group discussion with renal transplant recipients. These were constructed into a questionnaire and were then administered to two renal transplant out-patients populations. Item responses of study sample 1 were subjected to principal components analysis (PCA) using varimax rotation to examine the structure of responses. In order to investigate the stability of the factor structure found in Study 1, item responses of the second sample were subjected to confirmatory factor analysis (CFA) using structural equation modelling.
RESULTS: PCA indicated six factors that accounted for 64.2% of the variance. With extraneous items omitted, the final questionnaire derived from Study 1 has 24 items clustered around five conceptual coherent factors: worry about transplant (22.1%), guilt regarding donor (11.9%), disclosure (9.58%), medication adherence (8.73%), and responsibility (6.63%). CFA on the final 24-item version of the TxEQ revealed that the resulting model was a good fit for the Study 2 data (RMSEA = 0.08, pclose =.005).
CONCLUSIONS: The TxEQ has potential application as a measure in the area of transplantation research. CFA demonstrated that the factor structure of the TxEQ is consistent across different renal transplant out-patients populations. Further research is currently in progress to assess other groups of transplant recipients and to examine its relationship to other measures.

Entities:  

Year:  2002        PMID: 12614493     DOI: 10.1348/135910702320645381

Source DB:  PubMed          Journal:  Br J Health Psychol        ISSN: 1359-107X


  22 in total

1.  Facial transplantation.

Authors:  Maria Siemionow; Yalcin Kulahci
Journal:  Semin Plast Surg       Date:  2007-11       Impact factor: 2.314

2.  Validation of the psychometrics properties of a French quality of life questionnaire among a cohort of renal transplant recipients less than one year.

Authors:  Davy Beauger; Dorothée Fruit; Claire Villeneuve; Marie-Laure Laroche; Elisabeth Jouve; Annick Rousseau; Laurent Boyer; Stéphanie Gentile
Journal:  Qual Life Res       Date:  2016-03-26       Impact factor: 4.147

Review 3.  Measuring patient-reported outcomes in solid organ transplant recipients: an overview of instruments developed to date.

Authors:  Irina Cleemput; Fabienne Dobbels
Journal:  Pharmacoeconomics       Date:  2007       Impact factor: 4.981

4.  Unintentional and intentional non-adherence to immunosuppressive medications in renal transplant recipients.

Authors:  Konstadina Griva; Hui Ling Michelle Neo; Anantharaman Vathsala
Journal:  Int J Clin Pharm       Date:  2018-06-06

Review 5.  Adherence to immunosuppression in adult heart transplant recipients: A systematic review.

Authors:  Tasmeen Hussain; Keira Nassetta; Linda C O'Dwyer; Jane E Wilcox; Sherif M Badawy
Journal:  Transplant Rev (Orlando)       Date:  2021-09-20       Impact factor: 3.943

Review 6.  Patient-Reported Outcome Measures for Adults With Kidney Disease: Current Measures, Ongoing Initiatives, and Future Opportunities for Incorporation Into Patient-Centered Kidney Care.

Authors:  Devika Nair; F Perry Wilson
Journal:  Am J Kidney Dis       Date:  2019-09-03       Impact factor: 8.860

7.  Prospective Changes in Health-Related Quality of Life and Emotional Outcomes in Kidney Transplantation over 6 Years.

Authors:  Konstadina Griva; Jan Stygall; Juan Hui Ng; Andrew Davenport; Mike J Harrison; Stanton Newman
Journal:  J Transplant       Date:  2011-07-21

8.  Differences in emotional responses in living and deceased donor kidney transplant patients.

Authors:  Tanja Zimmermann; Selma Pabst; Anna Bertram; Mario Schiffer; Martina de Zwaan
Journal:  Clin Kidney J       Date:  2016-03-24

9.  Patient experiences with self-monitoring renal function after renal transplantation: results from a single-center prospective pilot study.

Authors:  Céline L van Lint; Paul Jm van der Boog; Wenxin Wang; Willem-Paul Brinkman; Ton Jm Rövekamp; Mark A Neerincx; Ton J Rabelink; Sandra van Dijk
Journal:  Patient Prefer Adherence       Date:  2015-12-07       Impact factor: 2.711

10.  The influence of sense of coherence on emotional response in heart transplant recipients - a preliminary report.

Authors:  Irena Milaniak; Ewa Wilczek-Rużyczka; Karol Wierzbicki; Jerzy Sadowski; Piotr Przybyłowski
Journal:  Kardiochir Torakochirurgia Pol       Date:  2014-06-29
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