| Literature DB >> 12613986 |
Stephen C Pflugfelder1, Abraham Solomon, Dilek Dursun, De-Quan Li.
Abstract
Dry eye may activate components of the ocular surface early warning system. Ocular surface stresses in dry eye, such as hyperosmolarity, could activate cellular stress pathways such as MAPKs. IL-1 and MMP-9 produced by the ocular surface epithelial cells may mediate initial events in the inflammatory cascade of dry eye through a dynamic interplay between them on the ocular surface.Entities:
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Year: 2002 PMID： 12613986 DOI： 10.1007/978-1-4615-0717-8_104
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622