| Literature DB >> 12613459 |
Svea Sallmann1, Antje Heilmann, Frank Heinke, Marie-Louise Kerkmann, Markus Schuppler, Gabriele Hahn, Manfred Gahr, Angela Rösen-Wolff, Joachim Roesler.
Abstract
Neutrophils of patients with chronic granulomatous disease (CGD) are profoundly defective in killing microorganisms. As in patients with chemotherapy-induced neutropenia, CGD patients are highly susceptible to life-threatening invasive Aspergillus infections, and conventional antimycotic treatment is not always successful. The new drug, caspofungin, was used to treat Aspergillus lung infection in one child with CGD.Entities:
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Year: 2003 PMID： 12613459
Source DB: PubMed Journal: Pediatr Infect Dis J ISSN： 0891-3668 Impact factor: 2.129