Literature DB >> 12613198

Ras signaling, deregulation of gene expression and oncogenesis.

Aylin S Ulkü, Channing J Der.   

Abstract

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Year:  2003        PMID: 12613198

Source DB:  PubMed          Journal:  Cancer Treat Res        ISSN: 0927-3042


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  12 in total

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4.  Oncogenic NRAS rapidly and efficiently induces CMML- and AML-like diseases in mice.

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6.  Ras-induced ROS upregulation affecting cell proliferation is connected with cell type-specific alterations of HSF1/SESN3/p21Cip1/WAF1 pathways.

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9.  Repression of sestrin family genes contributes to oncogenic Ras-induced reactive oxygen species up-regulation and genetic instability.

Authors:  Pavel B Kopnin; Larissa S Agapova; Boris P Kopnin; Peter M Chumakov
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