Literature DB >> 12612871

Undertreatment of hyperlipidemia in patients with coronary artery disease and heart failure.

Carla A Sueta1, Mark W Massing, Mridul Chowdhury, David P Biggs, Ross J Simpson.   

Abstract

BACKGROUND: Coronary artery disease patients with heart failure (CAD+HF) are at high risk for cardiovascular events. We examined the frequency of lipid assessment and prescription of lipid-lowering agents in outpatients with combined CAD+HF compared with patients with CAD alone.
METHODS: We analyzed an administrative data set from the Quality Assurance Program II, a Merck & Co., Inc., sponsored national retrospective chart audit of 41,487 CAD patients seen at 296 ambulatory medical practices. About 34% of these patients had CAD+HF.
RESULTS: Documentation of low-density lipoprotein (LDL) cholesterol was significantly lower in patients with CAD+HF (53%) compared with those with CAD alone (69%). Lipid-lowering drugs were prescribed in only 36% of patients with CAD+HF, compared with 52% of patients with CAD alone. Lipid levels alone did not justify this disparity. Patients with documented LDL cholesterol values were 4 times more likely to receive a prescription for a lipid-lowering medication than those without recorded values. Other predictors of lipid-lowering prescription included: younger age, history of myocardial infarction, revascularization, care by a cardiologist, and geographic region.
CONCLUSIONS: Patients with CAD, HF, and advanced age simultaneously experience among the highest risk and the lowest lipid-lowering treatment rates. Strategies to increase LDL testing and aggressively treat patients with heart failure and CAD are warranted.

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Year:  2003        PMID: 12612871     DOI: 10.1054/jcaf.2003.5

Source DB:  PubMed          Journal:  J Card Fail        ISSN: 1071-9164            Impact factor:   5.712


  6 in total

Review 1.  Coronary heart disease risk factors and outcomes in the twenty-first century: findings from the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study.

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Journal:  Curr Hypertens Rep       Date:  2015-04       Impact factor: 5.369

2.  Statin use after acute myocardial infarction: a nationwide study in Denmark.

Authors:  Jeppe N Rasmussen; Gunnar H Gislason; Steen Z Abildstrom; Søren Rasmussen; Ida Gustafsson; Pernille Buch; Jens Friberg; Lars Køber; Christian Torp-Pedersen; Mette Madsen; Steen Stender
Journal:  Br J Clin Pharmacol       Date:  2005-08       Impact factor: 4.335

3.  Patient-reported racial/ethnic healthcare provider discrimination and medication intensification in the Diabetes Study of Northern California (DISTANCE).

Authors:  Courtney R Lyles; Andrew J Karter; Bessie A Young; Clarence Spigner; David Grembowski; Dean Schillinger; Nancy Adler
Journal:  J Gen Intern Med       Date:  2011-05-06       Impact factor: 5.128

4.  Why don't diabetes patients achieve recommended risk factor targets? Poor adherence versus lack of treatment intensification.

Authors:  Julie A Schmittdiel; Connie S Uratsu; Andrew J Karter; Michele Heisler; Usha Subramanian; Carol M Mangione; Joe V Selby
Journal:  J Gen Intern Med       Date:  2008-03-04       Impact factor: 5.128

5.  Improving treatment intensification to reduce cardiovascular disease risk: a cluster randomized trial.

Authors:  Joe V Selby; Julie A Schmittdiel; Bruce Fireman; Marc Jaffe; Laura J Ransom; Wendy Dyer; Connie S Uratsu; Mary E Reed; Eve A Kerr; John Hsu
Journal:  BMC Health Serv Res       Date:  2012-07-02       Impact factor: 2.655

6.  Disparities in lipid management for African Americans and Caucasians with coronary artery disease: a national cross-sectional study.

Authors:  Mark W Massing; Kathleen A Foley; Lori Carter-Edwards; Carla A Sueta; Charles M Alexander; Ross J Simpson
Journal:  BMC Cardiovasc Disord       Date:  2004-08-18       Impact factor: 2.298

  6 in total

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