| Literature DB >> 12612745 |
Xisto Sena Passos1, Suzana da Costa Santos, Pedro Henrique Ferri, Orionalda de Fátima Lisboa Fernandes, Thaliana de Freitas Paula, Ana Cristina Ferreira Garcia, Maria do Rosário Rodrigues Silva.
Abstract
The widespread occurrence of cryptococcosis mainly in immunocompromised patients and the side effects of available drugs which are effective against this mycosis have led investigators to search for new antimycotic agents. Caryocar brasiliensis derived compounds were investigated against Cryptococcus neoformans using the agar dilution method. Based on MIC values, the best results were obtained with a concentration of < 250 g/mL of cuticular waxes of the Caryocar brasiliensis leaf collected during the dry period (170.8mm of precipitation) which inhibited the growth of 91.3% (21/23) Cryptococcus neoformans isolates.Entities:
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Year: 2003 PMID: 12612745 DOI: 10.1590/s0037-86822002000600013
Source DB: PubMed Journal: Rev Soc Bras Med Trop ISSN: 0037-8682 Impact factor: 1.581