Literature DB >> 12612420

A new stilbene with tyrosinase inhibitory activity from Chlorophora excelsa.

Kuniyoshi Shimizu1, Seiji Yasutake, Ryuichiro Kondo.   

Abstract

A new stilbene, 4-[(2"E)-7"-hydroxy-3",7"-dimethyloct-2"-enyl]-2',3,4',5-tetrahydroxy-trans-stilbene (1), and the known compound chlorophorin (2) were isolated from the heartwood of Chlorophora excelsa. Both 1 and 2 showed tyrosinase inhibitory activity with IC(50) values of 96 and 1.3 microM, respectively.

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Year:  2003        PMID: 12612420     DOI: 10.1248/cpb.51.318

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  8 in total

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2.  Discovery of highly potent tyrosinase inhibitor, T1, with significant anti-melanogenesis ability by zebrafish in vivo assay and computational molecular modeling.

Authors:  Wang-Chuan Chen; Tien-Sheng Tseng; Nai-Wan Hsiao; Yun-Lian Lin; Zhi-Hong Wen; Chin-Chuan Tsai; Yu-Ching Lee; Hui-Hsiung Lin; Keng-Chang Tsai
Journal:  Sci Rep       Date:  2015-01-23       Impact factor: 4.379

3.  Dopamine-Mediated Vanillin Multicomponent Derivative Synthesis via Grindstone Method: Application of Antioxidant, Anti-Tyrosinase, and Cytotoxic Activities.

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4.  The Combination of Niacinamide, Vitamin C, and PDRN Mitigates Melanogenesis by Modulating Nicotinamide Nucleotide Transhydrogenase.

Authors:  Hyun Jun Park; Kyung-A Byun; Seyeon Oh; Hyoung Moon Kim; Moon Suk Chung; Kuk Hui Son; Kyunghee Byun
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Review 5.  An updated review of tyrosinase inhibitors.

Authors:  Te-Sheng Chang
Journal:  Int J Mol Sci       Date:  2009-05-26       Impact factor: 6.208

6.  The antityrosinase and antioxidant activities of flavonoids dominated by the number and location of phenolic hydroxyl groups.

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Journal:  Chin Med       Date:  2018-10-19       Impact factor: 5.455

7.  Mechanistic studies of anti-hyperpigmentary compounds: elucidating their inhibitory and regulatory actions.

Authors:  Rosanna Y Y Lam; Zhi-Xiu Lin; Elena V Sviderskaya; Christopher H K Cheng
Journal:  Int J Mol Sci       Date:  2014-08-21       Impact factor: 5.923

8.  Isolation and Quantification of Ginsenoside Rh23, a New Anti-Melanogenic Compound from the Leaves of Panax ginseng.

Authors:  Dae Young Lee; Hyoung-Geun Kim; Yeong-Geun Lee; Jin Hee Kim; Jae Won Lee; Bo-Ram Choi; In-Bae Jang; Geum-Soog Kim; Nam-In Baek
Journal:  Molecules       Date:  2018-01-29       Impact factor: 4.411

  8 in total

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