Literature DB >> 12610878

[A patient with stage IVb small cell carcinoma of the esophagus who survived 23 months after systemic cancer chemotherapy].

Masanori Tsujie1, Nobuhiro Shibata, Takashi Nomura, Toshikazu Tanaka, Takashi Morimoto, Syoichi Fujita, Kotaro Kitani, Shin Nakahira, Hiroshi Okuda, Masashi Takeda.   

Abstract

A 59-year-old male visited our hospital with complaints of difficulty in swallowing. X-ray barium studies and upper gastrointestinal endoscopic examination revealed an irregular ulcerated lesion in the lower portion of the esophagus, which was diagnosed based on pathology tests as small cell carcinoma. A computed tomography scan showed para-aortic lymph node swelling and multiple liver metastases. Treatment with chemotherapy of CDDP and 5-FU showed clinical complete remission. However, the patient died of paraaortic lymph node metastasis, recurrence of the original lesion, multiple liver metastasis and brain metastasis 23 months after diagnosis. The prognosis of small cell carcinoma of the esophagus is quite unfavorable because of the highly aggressive biological behavior. However, if remission is achieved by chemotherapy as in this case, a better prognosis is possible.

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Year:  2003        PMID: 12610878

Source DB:  PubMed          Journal:  Gan To Kagaku Ryoho        ISSN: 0385-0684


  2 in total

1.  Small cell carcinoma of the esophagus responding to fourth-line chemotherapy with weekly paclitaxel.

Authors:  Masaki Matsuoka; Narikazu Boku; Takayuki Yoshino; Shuichi Hironaka; Yusuke Onozawa; Akira Fukutomi; Sadamoto Zenda; Kentaro Yamazaki; Hirofumi Yasui; Noriaki Hasuike; Tetsuya Inui; Yuichiro Yamaguchi; Hiroyuki Ono; Minoru Kamata
Journal:  Int J Clin Oncol       Date:  2005-12       Impact factor: 3.402

2.  Second-line chemotherapy for refractory small cell neuroendocrine carcinoma of the esophagus that relapsed after complete remission with irinotecan plus cisplatin therapy: Case report and review of the literature.

Authors:  Shinsuke Funakoshi; Akinori Hashiguchi; Kana Teramoto; Naoteru Miyata; Satoshi Kurita; Masayuki Adachi; Yasuo Hamamoto; Hajime Higuchi; Hiromasa Takaishi; Toshifumi Hibi
Journal:  Oncol Lett       Date:  2012-10-30       Impact factor: 2.967

  2 in total

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