Literature DB >> 12609548

A sensitive bioassay for chicken interleukin-18 based on the inducible release of preformed interferon-gamma.

Florian Puehler1, Thomas Göbel, Ulrike Breyer, Annette Ohnemus, Peter Staeheli, Bernd Kaspers.   

Abstract

Conventional tests for measuring the biological activity of chicken interleukin (IL)-18 require primary chicken spleen cells. We now describe a sensitive bioassay that is based on interleukin-18-induced release of interferon (IFN)-gamma by a permanent chicken cell line. In B19-2D8 cells, cytoplasmically stored interferon-gamma is quickly secreted in response to interleukin-18 exposure.

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Year:  2003        PMID： 12609548     DOI： 10.1016/s0022-1759(02)00515-x

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN： 0022-1759            Impact factor:   2.303


  4 in total

1.  The chicken leukocyte receptor complex encodes a primordial, activating, high-affinity IgY Fc receptor.

Authors:  Birgit C Viertlboeck; Sonja Schweinsberg; Matthias A Hanczaruk; Ramona Schmitt; Louis Du Pasquier; Friedrich W Herberg; Thomas W Göbel
Journal:  Proc Natl Acad Sci U S A       Date:  2007-07-02       Impact factor: 11.205

2.  A eukaryotic expression plasmid carrying chicken interleukin-18 enhances the response to newcastle disease virus vaccine.

Authors:  Chen Wang; Xiaokang Li; Chunjie Zhang; Tingcai Wu; Yinju Li; Xiangchao Cheng
Journal:  Clin Vaccine Immunol       Date:  2014-10-29

3.  Chicken TREM-B1, an Inhibitory Ig-Like Receptor Expressed on Chicken Thrombocytes.

Authors:  Vanessa Turowski; Beatrice Sperling; Matthias A Hanczaruk; Thomas W Göbel; Birgit C Viertlboeck
Journal:  PLoS One       Date:  2016-03-11       Impact factor: 3.240

4.  Molecular cloning and characterisation of chicken IL-18 binding protein.

Authors:  Mark S Gibson; Angela Steyn; David Kealy; Bernd Kaspers; Mark S Fife
Journal:  Dev Comp Immunol       Date:  2020-09-09       Impact factor: 3.636
  4 in total

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