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Literature DB >> 12608859

New cytotoxic furanosesterterpenes from an Okinawan marine sponge, Ircinia sp.

Hamad H Issa¹, Junichi Tanaka, Tatsuo Higa.

Abstract

Five new sesterterpenes have been isolated from a lipophilic extract of a sponge, Ircinia sp., and their structures elucidated by spectroscopic and chemical methods. The absolute configurations of two metabolites (1, 3) were established by chemical degradation. These compounds showed moderate cytotoxicity against KB cells.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2003 PMID： 12608859 DOI： 10.1021/np020456p

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

6 in total

1. Monitoring bacterial diversity of the marine sponge Ircinia strobilina upon transfer into aquaculture.

Authors: Naglaa M Mohamed; Venkateswara Rao; Mark T Hamann; Michelle Kelly; Russell T Hill
Journal: Appl Environ Microbiol Date: 2008-05-09 Impact factor: 4.792

2. Furanoterpene Diversity and Variability in the Marine Sponge Spongia officinalis, from Untargeted LC-MS/MS Metabolomic Profiling to Furanolactam Derivatives.

Authors: Cléa Bauvais; Natacha Bonneau; Alain Blond; Thierry Pérez; Marie-Lise Bourguet-Kondracki; Séverine Zirah
Journal: Metabolites Date: 2017-06-13

3. Discovery of Ircinianin Lactones B and C-Two New Cyclic Sesterterpenes from the Marine Sponge Ircinia wistarii.

Authors: Thomas Majer; Keshab Bhattarai; Jan Straetener; Justus Pohlmann; Patrick Cahill; Markus O Zimmermann; Marc P Hübner; Marcel Kaiser; Johan Svenson; Michael Schindler; Heike Brötz-Oesterhelt; Frank M Boeckler; Harald Gross
Journal: Mar Drugs Date: 2022-08-19 Impact factor: 6.085

New cytotoxic furanosesterterpenes from an Okinawan marine sponge, Ircinia sp.

1. Monitoring bacterial diversity of the marine sponge Ircinia strobilina upon transfer into aquaculture.

2. Furanoterpene Diversity and Variability in the Marine Sponge Spongia officinalis, from Untargeted LC-MS/MS Metabolomic Profiling to Furanolactam Derivatives.

3. Discovery of Ircinianin Lactones B and C-Two New Cyclic Sesterterpenes from the Marine Sponge Ircinia wistarii.

4. Diastereodivergent organocatalysis for the asymmetric synthesis of chiral annulated furans.

5. New 9α-Hydroxy-5α,6α-epoxyhydroxysterols from the Vietnamese Marine Sponge Ircinia echinata.

6. Unique Polyhalogenated Peptides from the Marine Sponge Ircinia sp.