| Literature DB >> 12608803 |
Irene M Lagoja1, Sylvie Pochet, Valerie Boudou, Roy Little, Eveline Lescrinier, Jef Rozenski, Piet Herdewijn.
Abstract
The synthesis of fully [13C/15N] labeled pyrimidine nucleosides has been achieved from 13C-glucose and labeled nucleobases. The reaction scheme leads directly to the protected nucleosides without the need for the inversion of configuration of C-3 of 13C-glucose. This was achieved by an oxitative ring-opening reaction removing the carbon with the wrong configuration.Entities:
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Year: 2003 PMID： 12608803 DOI： 10.1021/jo0205098
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354