Literature DB >> 12607658

Clinical impact of drug-eluting stents in changing referral practices for coronary surgical revascularization in a tertiary care center.

Alexandre C Ferreira1, Arley A Peter, Tomas A Salerno, Hooshang Bolooki, Eduardo de Marchena.   

Abstract

BACKGROUND: The long-term benefits of angioplasty are limited by the occurrence of restenosis. Drug-eluting stents with a projected restenosis rate of close to 0% are soon to become available. The short- and long-term consequences of this advance to the cardiac surgical volume remain unclear.
METHODS: A total of 196 consecutive coronary angiograms and medical records of patients referred for coronary bypass surgery were reviewed. Considering the hypothetical premise of having drug-eluting stents with a near zero restenosis rate, we reviewed each case to determine if surgical revascularization was still the preferred option for revascularization.
RESULTS: The mean age was 60 (+/-10.6) years. Seventy-two percent of patients were male. Considering the availability of drug-eluting stents 154 (79%) would still have been sent to surgery, representing a 21% decrease in the number of surgical revascularizations. Angiographic characteristics predicting coronary bypass revascularization were the presence of chronic total occlusion (odds ratio [OR]: 9.1; confidence interval [CI]: 2.1 to 39), left main coronary artery stenosis (OR: 9.6; CI: 1.27 to 73), and need for valvular surgery (OR: 7.38; CI: 1.3 to 157). The most common predictors of a change in clinical management from surgical to percutaneous revascularization if drug-eluting stents were available were diffuse coronary narrowing (OR: 15.78), restenotic lesions (OR: 27.86), and small coronary arteries (OR: 26).
CONCLUSIONS: Drug-eluting stents may have a significant impact on cardiac surgery volume (approximately a 21% decrease in our center). It may also direct patients with small vessels, diffuse narrowing, or restenotic lesions and diabetic patients to percutaneous therapy.

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Year:  2003        PMID: 12607658     DOI: 10.1016/s0003-4975(02)04367-9

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  5 in total

Review 1.  [Drug-eluting stents: implications for modern coronary revascularization].

Authors:  A Martens; A Haverich
Journal:  Chirurg       Date:  2009-06       Impact factor: 0.955

2.  Recent evolution in demographic and clinical characteristics and in-hospital morbidity in patients undergoing coronary surgery.

Authors:  Richard G Baillot; Denis R Joanisse; Louis Mathieu Stevens; Daniel P Doyle; Brigitte Dionne; François Lellouche
Journal:  Can J Surg       Date:  2009-10       Impact factor: 2.089

Review 3.  [When are drug-eluting stents effective? A critical analysis of the presently available data].

Authors:  S Silber
Journal:  Z Kardiol       Date:  2004-09

4.  Immediate Postoperative Complications in Patients Undergoing CABG; Investigating the Role of Prior Coronary Stenting.

Authors:  Sohrab Negargar; Shahriar Anvari; Kyomars Abbasi; Elgar Enamzadeh
Journal:  J Cardiovasc Thorac Res       Date:  2014-12-30

5.  Neurological complications are avoidable during CABG.

Authors:  Zulfiqar Haider; Anjum Jalal; Asif Rashid Alamgir; Irfan Rasheed
Journal:  Pak J Med Sci       Date:  2018 Jan-Feb       Impact factor: 1.088

  5 in total

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