Literature DB >> 12605487

Simplakidine A, a unique pyridinium alkaloid from the Caribbean sponge plakortis simplex.

Claudio Campagnuolo1, Caterina Fattorusso, Ernesto Fattorusso, Angela Ianaro, Barbara Pisano, Orazio Taglialatela-Scafati.   

Abstract

Simplakidine A, a unique 4-alkyl-substituted pyridiunium alkaloid, has been isolated from the Caribbean sponge Plakortis simplex. The stereostructure of simplakidine A has been determined using MS and NMR data, molecular mechanics, and an extension of the J-based configuration analysis. Data about the growth-inhibition activity of simplakidine A are reported.

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Year:  2003        PMID: 12605487     DOI: 10.1021/ol027437r

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  4 in total

1.  Highly diastereoselective Pd-catalyzed carboetherification reactions of acyclic internal alkenes. Stereoselective synthesis of polysubstituted tetrahydrofurans.

Authors:  Amanda F Ward; John P Wolfe
Journal:  Org Lett       Date:  2010-03-19       Impact factor: 6.005

2.  Synthesis of polysubstituted tetrahydrofurans via Pd-catalyzed carboetherification reactions.

Authors:  Michael B Hay; John P Wolfe
Journal:  Tetrahedron Lett       Date:  2006-04-17       Impact factor: 2.415

3.  Pyridylic anions are soft nucleophiles in the palladium-catalyzed C(sp3)-H allylation of 4-alkylpyridines.

Authors:  Nour Wasfy; Faizan Rasheed; Raphaël Robidas; Isabelle Hunter; Jiaqi Shi; Brian Doan; Claude Y Legault; Dan Fishlock; Arturo Orellana
Journal:  Chem Sci       Date:  2020-12-10       Impact factor: 9.825

4.  Simplexidine, a 4-alkylpyridinium alkaloid from the Caribbean sponge Plakortis simplex.

Authors:  Ernesto Fattorusso; Adriana Romano; Fernando Scala; Orazio Taglialatela-Scafati
Journal:  Molecules       Date:  2008-07-17       Impact factor: 4.411

  4 in total

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