| Literature DB >> 12605474 |
Tiffany Malinky Gierasch1, Zhangjie Shi, Gregory L Verdine.
Abstract
The syntheses of stereodiverse libraries of 12 and 19 are reported, where each asterisk represents an independently varied stereocenter. These scaffolds provide additional templates for investigations of geometric diversity in library syntheses. Libraries of these N-Fmoc-amino acids were further functionalized by incorporation into a peptide sequence, demonstrating the utility of 12 and 19 as building blocks for diversity oriented synthesis.Entities:
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Year: 2003 PMID： 12605474 DOI： 10.1021/ol027116f
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005