| Literature DB >> 12605373 |
Iris Bittmann1, Burkhard Rolf, Gudrun Amann, Udo Löhrs.
Abstract
Lymphangioleiomyomatosis (LAM) is a rare disease found primarily in white women of childbearing age. The present study describes a case of recurrent LAM after single lung transplantation. Double-staining nonisotopic in situ hybridization, immunohistochemistry, and short tandem repeat loci analysis demonstrated that the recurrent LAM lesions originated from the recipient. The data strongly support that metastatic spread of LAM cells or migration of progenitor cells plays an important role in the pathogenesis of LAM. Copyright 2003, Elsevier Science (USA). All rights reserved.Entities:
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Year: 2003 PMID： 12605373 DOI： 10.1053/hupa.2003.50
Source DB: PubMed Journal: Hum Pathol ISSN： 0046-8177 Impact factor: 3.466