Literature DB >> 12605320

Silica-related rheumatoid arthritis without lung involvement.

D Markovits1, D Schapira, A Wiener, A M Nahir.   

Abstract

We report a young male with recent onset of rheumatoid arthritis (RA) in whom the remarkable severity of the disease led to additional investigations. The only significant finding was mediastinal lymphadenopathy, without lung involvement. Biopsy of the mediastinal lymph node revealed pathological findings typical of silicosis. To our knowledge, this is the first report of silicosis apparent solely in the mediastinal lymph node of an RA patient. This suggests that lung involvement is not crucial for the development of silica-related arthritis.

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Year:  2003        PMID: 12605320     DOI: 10.1007/s10067-002-0639-4

Source DB:  PubMed          Journal:  Clin Rheumatol        ISSN: 0770-3198            Impact factor:   2.980


  2 in total

1.  Silicotic mediastinal lymphadenopathy can cause left vocal cord paralysis and dysphagia.

Authors:  Ulrich F Vogel; Christina Pfannenberg; Thomas Renck; Dietrich Müller-Wening; Burkhard Bültmann
Journal:  Virchows Arch       Date:  2007-07-13       Impact factor: 4.064

2.  Silicon, a Possible Link between Environmental Exposure and Autoimmune Diseases: The Case of Rheumatoid Arthritis.

Authors:  Cesar A Speck-Hernandez; Gladis Montoya-Ortiz
Journal:  Arthritis       Date:  2012-10-18
  2 in total

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