Literature DB >> 12605112

Comprehensive cost comparison of adult-adult right hepatic lobe living-donor liver transplantation with cadaveric transplantation.

James F Trotter1, Scott Mackenzie, Michael Wachs, Thomas Bak, Tracy Steinberg, Patty Polsky, Igal Kam, Gregory T Everson.   

Abstract

BACKGROUND: An important long-term consideration for living-donor liver transplantation (LDLT) is the expense compared with cadaveric-liver transplantation. LDLT is a more complex procedure than cadaveric transplantation and the cost of donor evaluation, donor surgery, and postoperative donor care must be included in a cost analysis for LDLT. In this study, we compare the comprehensive cost of LDLT with that of cadaveric-liver transplantation.
METHODS: All costs for medical services provided at our institution were recorded for 24 LDLT and 43 cadaveric recipients with greater than 1 year follow-up transplanted between August 1997 and April 2000. The donor costs include donors evaluated and rejected, donors evaluated and accepted, donor right hepatectomy costs, and donor follow-up costs (365 days postdonation). LDLT and cadaveric recipient costs include medical care 90 days pre-LDLT, recipient transplant costs, and recipient follow-up costs (365 days posttransplant) including retransplantation. Cost is expressed as an arbitrary cost unit (CU) that is a value between $500 to $1,500.
RESULTS: Total LDLT costs (evaluations of rejected donors+evaluations of accepted donors+donor hepatectomy+donor follow-up care for 1 year+pretransplant recipient care [90 days pretransplant]+recipient transplantation+recipient 1-year posttransplant care)= 162.7 CU. Total mean cadaveric transplant costs (pretransplant recipient care [90 days pretransplant]+recipient transplantation [including organ acquisition cost]+recipient 1-year posttransplant care)= 134.5 CU, (P =ns).
CONCLUSIONS: The total comprehensive cost of LDLT is 21% higher than cadaveric transplantation, although this difference is not significant.

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Year:  2003        PMID: 12605112     DOI: 10.1097/01.TP.0000047310.04069.ED

Source DB:  PubMed          Journal:  Transplantation        ISSN: 0041-1337            Impact factor:   4.939


  5 in total

1.  The relative net health benefit of liver resection, ablation, and transplantation for early hepatocellular carcinoma.

Authors:  Gaya Spolverato; Alessandro Vitale; Aslam Ejaz; Yuhree Kim; Shishir K Maithel; David P Cosgrove; Timothy M Pawlik
Journal:  World J Surg       Date:  2015-06       Impact factor: 3.352

2.  [Living donor liver transplantation in adults].

Authors:  U P Neumann; P Neuhaus; M Schmeding
Journal:  Chirurg       Date:  2010-09       Impact factor: 0.955

3.  Addition of adult-to-adult living donation to liver transplant programs improves survival but at an increased cost.

Authors:  Patrick G Northup; Michael M Abecassis; Michael J Englesbe; Jean C Emond; Vanessa D Lee; George J Stukenborg; Lan Tong; Carl L Berg
Journal:  Liver Transpl       Date:  2009-02       Impact factor: 5.799

Review 4.  Live donors in liver transplantation.

Authors:  Robert S Brown
Journal:  Gastroenterology       Date:  2008-05       Impact factor: 22.682

Review 5.  Domino Hepatocyte Transplantation: A Therapeutic Alternative for the Treatment of Acute Liver Failure.

Authors:  Liana Monteiro da Fonseca Cardoso; Lucio Filgueiras Pacheco Moreira; Marcelo Alves Pinto; Andrea Henriques-Pons; Luiz Anastácio Alves
Journal:  Can J Gastroenterol Hepatol       Date:  2018-07-02
  5 in total

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