| Literature DB >> 12604130 |
Lisa Licitra1, Jacques Bernier, Esteban Cvitkovic, Cesare Grandi, Silvia Spinazzé, Paolo Bruzzi, Gemma Gatta, Roberto Molinari.
Abstract
Nasopharyngeal cancer (NPC) is quite rare throughout Europe, accounting for an annual incidence rate below 1 per 100.000, whereas the highest risk area is South East Asia. A predominant occurrence in males is to be noted. NPC is an etiologically multifactorial disease, most probably involving viral, genetic and environmental factors. Carcinomas of the nasopharynx can be divided into two major histotypes: keratinizing squamous cell carcinomas (WHO-type 1) and non-keratinizing carcinomas (WHO-type 2). The histological type is a prognostic factor and it has a clear impact on the outcome of treatment. Standard therapeutic option for early stages of NPC is radiation, while an integration of radiation therapy and chemotherapy is indicated in more advanced stages.Entities:
Mesh：
Year: 2003 PMID： 12604130 DOI： 10.1016/s1040-8428(01)00210-4
Source DB: PubMed Journal: Crit Rev Oncol Hematol ISSN： 1040-8428 Impact factor: 6.312