| Literature DB >> 12604032 |
R M Abra1, R B Bankert, F Chen, N K Egilmez, K Huang, R Saville, J L Slater, M Sugano, S J Yokota.
Abstract
Three topics are discussed. Enhanced anti-tumor efficacy of targeted doxorubicin-containing sterically-stabilized liposomes using an anti-beta1 integrin Fab' ligand. Use of tumor targeting with an internalizing ligand to improve the efficacy of a non-leaky cisplatin-containing sterically-stabilized liposome formulation. Formulation variables (remote-loading with dextran ammonium sulfate, rigid lipid bilayer) used to optimize in vivo performance of a liposomal camptothecin analog.Entities:
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Year: 2002 PMID: 12604032 DOI: 10.1081/lpr-120004770
Source DB: PubMed Journal: J Liposome Res ISSN: 0898-2104 Impact factor: 3.648