Literature DB >> 12603057

Methods for analysis and visualization of SNP genotype data for complex diseases.

Anya Tsalenko1, Amir Ben-Dor, Nancy Cox, Zohar Yakhini.   

Abstract

SNP markers are becoming central for studying genetic determinants of complex diseases. Large SNP data collected in such studies call for the development of specialized analysis tools. We present methods for selecting sets of SNPs that can be associated to sample properties in case/control studies. We also describe how scoring and selection can be statistically tested. This is done at the single locus as well as at the set level.

Mesh：

Year:  2003        PMID： 12603057     DOI： 10.1142/9789812776303_0051

Source DB:  PubMed          Journal:  Pac Symp Biocomput        ISSN： 2335-6928


  4 in total

1.  Reconstructability analysis as a tool for identifying gene-gene interactions in studies of human diseases.

Authors:  Stephen Shervais; Patricia L Kramer; Shawn K Westaway; Nancy J Cox; Martin Zwick
Journal:  Stat Appl Genet Mol Biol       Date:  2010-03-03

2.  Genetic variation in putative regulatory loci controlling gene expression in breast cancer.

Authors:  Vessela N Kristensen; Hege Edvardsen; Anya Tsalenko; Silje H Nordgard; Therese Sørlie; Roded Sharan; Aditya Vailaya; Amir Ben-Dor; Per Eystein Lønning; Sigbjørn Lien; Stig Omholt; Ann-Christine Syvänen; Zohar Yakhini; Anne-Lise Børresen-Dale
Journal:  Proc Natl Acad Sci U S A       Date:  2006-05-09       Impact factor: 11.205

3.  Gefitinib in Combination with Weekly Docetaxel in Patients with Metastatic Breast Cancer Caused Unexpected Toxicity: Results from a Randomized Phase II Clinical Trial.

Authors:  Olav Engebraaten; Hege Edvardsen; Erik Løkkevik; Bjørn Naume; Vessela Kristensen; Lars Ottestad; Vasanti Natarajan
Journal:  ISRN Oncol       Date:  2012-05-14

4.  Multilocus analysis of SNP and metabolic data within a given pathway.

Authors:  Vessela N Kristensen; Anya Tsalenko; Jurgen Geisler; Anne Faldaas; Grethe Irene Grenaker; Ole Christian Lingjaerde; Ståle Fjeldstad; Zohar Yakhini; Per Eystein Lønning; Anne-Lise Børresen-Dale
Journal:  BMC Genomics       Date:  2006-01-13       Impact factor: 3.969
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.