Literature DB >> 12602628

Potential health risks due to toxic contamination in the ambient environment of certain Indian states.

B R Gurjar1, Manju Mohan.   

Abstract

Toxic or hazardous substances pose two types of risks in the environment, namely 'short-term or acute risk' and 'long-term or chronic risk'. The short-term risk is associated with the one-time acute exposure to potentially hazardous substances accidentally released in the environment, whereas the long-term risk is resulted from continuous exposure to potentially harmful substances present in different environmental media. This article deals with the assessment of potential health risks related to certain carcinogens and non-carcinogens (e.g. cadmium, chromium and nickel) present in three environmental media, viz. air, water and food in different Indian states (regions). Appropriate dose-response models have been identified and used for this purpose with the assumptions and input data as per the Indian context. Mean values of ambient air concentration levels of Cd, Cr and Ni have been used to estimate the individual and societal risks of extra cancer in different states of India. The hazard quotients and hazard index representing the non-carcinogenic chronic health effects caused by chromium and cadmium due to their long-term exposure through water and food have also been estimated. The risk results have been compared with the disease surveillance data. A definite correlation between the estimated risk results and the reported number of lung cancer cases and chronic liver diseases have been observed in different regions. As a matter of fact, it is not possible to derive precise risk estimates due to various uncertainties included both in available data and in the models which are used to calculate potency factors and effective concentration. However, average risk levels as estimated and presented in this article are quite useful for planning purposes.

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Year:  2003        PMID: 12602628     DOI: 10.1023/a:1021886116208

Source DB:  PubMed          Journal:  Environ Monit Assess        ISSN: 0167-6369            Impact factor:   2.513


  7 in total

1.  Standard setting processes and regulations for environmental contaminants in drinking water: state versus federal needs and viewpoints.

Authors:  K S Sidhu
Journal:  Regul Toxicol Pharmacol       Date:  1991-06       Impact factor: 3.271

2.  Potential health risks related to carcinogens in the atmospheric environment in India.

Authors:  B R Gurjar; M Mohan; K S Sidhu
Journal:  Regul Toxicol Pharmacol       Date:  1996-10       Impact factor: 3.271

3.  Cancers of the lung and nasal sinuses in nickel workers: a reassessment of the period of risk.

Authors:  R Doll; J D Mathews; L G Morgan
Journal:  Br J Ind Med       Date:  1977-05

4.  Inhibitory effect of manganese upon muscle tumorigenesis by nickel subsulfide.

Authors:  F W Sunderman; T J Lau; L J Cralley
Journal:  Cancer Res       Date:  1974-01       Impact factor: 12.701

Review 5.  Chromium occurrence and function in biological systems.

Authors:  W Mertz
Journal:  Physiol Rev       Date:  1969-04       Impact factor: 37.312

6.  Daily intake of lead, cadmium, copper, and zinc from drinking water: The Seattle Study of Trace Metal Exposure.

Authors:  A R Sharrett; A P Carter; R M Orheim; M Feinleib
Journal:  Environ Res       Date:  1982-08       Impact factor: 6.498

7.  Estimate of cancer incidence in India in 1991.

Authors:  D N Rao; B Ganesh
Journal:  Indian J Cancer       Date:  1998-03       Impact factor: 1.224

  7 in total

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