OBJECTIVE: The study goal was to evaluate the use of combined positron emission tomography/computed tomography (PET/CT) imaging for localization of recurrent disease in thyroid cancer patients. STUDY DESIGN AND SETTING: Eight patients with suspected recurrence of thyroid cancer on the basis of elevated serum thyroglobulin or calcitonin levels underwent combined PET/CT imaging on a prototype device. All 8 patients had previously undergone total thyroidectomy and (131)I ablation for thyroid carcinoma. Patients with papillary carcinoma had negative (131)I scans. RESULTS: Eight patients underwent combined PET/CT scanning. Four (50%) of 8 patients underwent PET/CT indicating recurrence in the head and neck. A total of 11 lesions in these 4 patients were suspicious for recurrence on combined PET/CT imaging. Three patients with 8 lesions suspicious for recurrence on PET/CT underwent surgical removal of disease. All 3 patients had pathologic confirmation of recurrence, with 6 (75.0%) of 8 lesions being positive. CONCLUSION: Combined PET/CT imaging is a valuable tool for the diagnosis and anatomic localization of recurrent thyroid cancer.
OBJECTIVE: The study goal was to evaluate the use of combined positron emission tomography/computed tomography (PET/CT) imaging for localization of recurrent disease in thyroid cancerpatients. STUDY DESIGN AND SETTING: Eight patients with suspected recurrence of thyroid cancer on the basis of elevated serum thyroglobulin or calcitonin levels underwent combined PET/CT imaging on a prototype device. All 8 patients had previously undergone total thyroidectomy and (131)I ablation for thyroid carcinoma. Patients with papillary carcinoma had negative (131)I scans. RESULTS: Eight patients underwent combined PET/CT scanning. Four (50%) of 8 patients underwent PET/CT indicating recurrence in the head and neck. A total of 11 lesions in these 4 patients were suspicious for recurrence on combined PET/CT imaging. Three patients with 8 lesions suspicious for recurrence on PET/CT underwent surgical removal of disease. All 3 patients had pathologic confirmation of recurrence, with 6 (75.0%) of 8 lesions being positive. CONCLUSION: Combined PET/CT imaging is a valuable tool for the diagnosis and anatomic localization of recurrent thyroid cancer.
Authors: Lutz S Freudenberg; Andrea Frilling; Hilmar Kühl; Stefan P Müller; Walter Jentzen; Andreas Bockisch; Gerald Antoch Journal: Eur Radiol Date: 2007-05-22 Impact factor: 5.315
Authors: Rita A Yeretsian; Todd M Blodgett; Barton F Branstetter; Michelle M Roberts; Carolyn C Meltzer Journal: AJNR Am J Neuroradiol Date: 2003 Jun-Jul Impact factor: 3.825
Authors: Joan Manel Gasent Blesa; Enrique Grande Pulido; Mariano Provencio Pulla; Vicente Alberola Candel; Juan Bautista Laforga Canales; Miguel Grimalt Arrom; Patricia Martin Rico Journal: J Thyroid Res Date: 2010-04-13