Literature DB >> 1260116

The measurement of diphenoxylic acid in plasma following administration of diphenoxylate.

G C Ford, N J Haskins, R F Palmer, M J Tidd, P H Buckley.   

Abstract

The measurement of diphenoxylic acid, the major metabolite of diphenoxylate, has been performed in man using a deuterium labelled internal standard and multiple ion monitoring using a gas chromatograph mass spectrometer. The determination of plasma concentrations following administration of diphenoxylate to man is described.

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Year:  1976        PMID: 1260116     DOI: 10.1002/bms.1200030109

Source DB:  PubMed          Journal:  Biomed Mass Spectrom        ISSN: 0306-042X


  2 in total

Review 1.  Clinical pharmacokinetics of drugs used in the treatment of gastrointestinal diseases (Part II).

Authors:  K Lauritsen; L S Laursen; J Rask-Madsen
Journal:  Clin Pharmacokinet       Date:  1990-08       Impact factor: 6.447

2.  Respiratory depression due to unsuspected narcotic ingestion treated with naloxone.

Authors:  D A Curnock
Journal:  Arch Dis Child       Date:  1978-06       Impact factor: 3.791

  2 in total

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